The absolute and unbridgeable separation among the realms of the non living, biophysical and human creativity points to the idea that rather than assuming that substance is merely located within those boundaries, substance is rather the movement from one to another.
The paradox of humanity's forever finite yet evolving knowledge of such infinitely powerful sources of universal creation rightfully situates the solution to the current baleful consequences of the false ideologies of geopolitics and limited resources.
For there can be no possible limits to human technological progress which revolutionizes the very definition of what constitutes a resource. The proof of this potential can only be grasped negatively in the same way that the ironic nature of substance is addressed above. While we as a species are constrained to operating within the confines of existing modes of sustenance, it is only when the necessary orientation of discovery permeates our science and art that we truly exhibit our whole and uniquely creative nature.
Eratosthenes first measured the circumference of the earth from the shadows cast by the sun. Today, humanity's fitness to survive will be measured by our ability to conquer that same thermonuclear fusion that casts those shadows. Thus, Prometheus will truly be unbound.