Random Noise or Crosstalk? God Still Doesn't Shoot Pool.

Here is an elegant insight that solves the apparent noise of random stochastics of pure chance at the biological signalling domain. Bravo!

Decision Making at a Subcellular Level Determines the Outcome of Bacteriophage Infection

Lanying Zeng,Samuel O. Skinner,Chenghang Zong,Jean Sippy,Michael Feiss,Ido GoldingSee Affiliations

• Summary
• Introduction
• Results
• Discussion
• Exp. Proc.
• Data
• References
• Supp. Info.
• Related Info.
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• • Graphical Abstract

  

• Highlights
• Each infecting λ phage makes an independent choice between lysis and lysogeny
• Cell lysogeny is pursued only if all infecting phages choose that fate
• The observed single-cell phenotype is much noisier than that of the single phage

• Summary
• When the process of cell-fate determination is examined at single-cell resolution, it is often observed that individual cells undergo different fates even when subject to identical conditions. This “noisy” phenotype is usually attributed to the inherent stochasticity of chemical reactions in the cell. Here we demonstrate how the observed single-cell heterogeneity can be explained by a cascade of decisions occurring at the subcellular level. We follow the postinfection decision in bacteriophage lambda at single-virus resolution, and show that a choice between lysis and lysogeny is first made at the level of the individual virus. The decisions by all viruses infecting a single cell are then integrated in a precise (noise-free) way, such that only a unanimous vote by all viruses leads to the establishment of lysogeny. By detecting and integrating over the subcellular “hidden variables,” we are able to predict the level of noise measured at the single-cell level.

Bankers In Euphoric Orgy: "Just Give Us the Dough, To Hell With Society"

Gotterbankerdammerung! What a ghoulish Walpurgisnacht! The IMF, ECB and Federal Reserve unleash hellhounds on the people forsooth.

A Classic Case of Manipulation of Misplaced Rage

The NY Post headline has a clarion tone this morning meant to enrage its dupe readers by misdirecting their palpable ire at Greece. "We're bailing out Greece--but US taxpayers shouldn't be" it screams. What a joke. As I point out in my retort:

What all the articles about Greece conveniently fail to mention is that the bailout will pass right through Greece to the creditor banks. Just like the $100 billion for AIG wound up in the pockets of financier bucket shop fraudsters like Goldman Sucks. I say put these international gambling casinos derivatives through chapter 11. Force through an international Glass Steagall now! The solution: Go back to sovereign fixed currencies and issue national credits for large scale infrastructure projects, etc.


Or you can't fool all the people all of the time.  Seems like almost every Post I survey these days has been despoiled by the vagrant dogs of the press.

Principled Vampires Need More Blood

The latest headline about Goldman Sachs perhaps reveals more than it would seem on the surface of things. Viz:"Blankfein Says Goldman Must Renew Core Principles" This reminds one of nothing so much as of the old gag about the literary difference between a shyster and a rooster who always clucks defiance.

Pseudoscience Mockery

Bladeless wind turbine inspired by Tesla

May 7, 2010 by Lisa Zyga

Enlarge

(Left) The bladeless wind turbine, and (right) the stack of disks which rotate and are connected to a shaft. Image credit: Solar Aero.

(PhysOrg.com) -- A bladeless wind turbine whose only rotating component is a turbine/driveshaft could generate power at a cost comparable to coal-fired power plants, according to its developers at Solar Aero. The New Hampshire-based company recently announced its patent on the Fuller wind turbine, which is an improvement on a patent issued to Nikola Tesla in 1913.

If one Googles Lisa Zyga one finds an astonishing array of the most arrant balderdash imaginable. This persona is obviously a hoaxer. For instance, "Scientists model words as entangled quantum states in our minds." Mr E.A. Poe gave us a number of such pranks in his day.

But then again, as the narrator, Cide Hamete Benegeli, of Don Quixote often fondly quoted Avicenna as saying: "The whole world is crazy." For instance, compare how Hawking's latest reveries on hostile aliens and time warps puts him in the same league with Newton's alchemical ravings that Keynes (quite the madman in his own right, you understand) unearthed.

More Anti-science Quackery

Statistical Physics Offers Insight Into Moral Behavior

May 6, 2010 by Miranda Marquit

(PhysOrg.com) -- It seems a little strange for statistical physicists to consider questions of morality in behavior. However, that is is just what a study at ETH in Zurich, Switzeralnd, is doing. Led by Dirk Helbing, the study used game theory to consider how moral behavior arises from interactions with neighbors. Instead of moral behavior developing from an individual's interactions with society as a whole, Helbing's group discovered that there is a good chance that interactions with the individuals nearest to a person lead to the development of moral behavior.

This is a laughable monstrosity of an "experiment." It is merely a rehashing of Adam Smith's moral relativism. Which is to say that mankind cannot take responsibility for the outcome of its primal drives. This is nothing but an apology for the immorality of an oligarchical elite (technocrats in today's vernacular) having its way with a bovine-like, brutish populace. It is the opposite of why America's constitutional republic was founded. We Americans, at least during our best administrations have been governed by the principle that future generations should hold us morally responsible for providing a legacy of something better... This has been the motto of immigrants to these shores from before our revolution. This reported sociological drivel is a mockery of true science.

Stephen Hawking: You're No Einstein!

Hostile aliens and time travel through wormholes. Ahem... Really? Dear professor and Royal Society member, I'm afraid if you don't get a grip soon, you'll end up burying amulets in your back yard to invoke chaos magic just like your "illustrious" predecessor Sir Isaac.

The Value of Money: All That Glitters Is Not Gold

Query: If a record $106.5 million is paid for a Picasso supposedly "depicting" a "nude and bust" childishly scrawled in a day by the obviously imbalanced "artist," what is the value of money to the crowd of financiers who prize such dross?

The answer is just this: They will burn one hundred million dollars on a lark one day and the next force thousands out of their homes and into the streets all in the name of fiscal responsibility. All honorable and upright citizens, you understand, it goes without saying.

Atheism Versus Intelligent Design: Another Dog and Pony Show

This so called debate here is inconsequential because both sides are looking for proof or disproof of some mechanism of divinity. Very sad. The human mind's historically verifiable increasing power over nature is a non mechanistic proof that that selfsame willful human creativity is uniquely sui generis. This is the truth in the biblical injunction that man take dominion over nature. Today that signifies the mission of colonizing space. Beyond that, all this dog and pony show of atheism versus intelligent design is so much unintelligible blather.

The Ugly Truth About Paul Krugman

So the Nobel laureate opines today thusly:

Consider what Greece would get if it simply stopped paying any interest or principal on its debt. All it would have to do then is run a zero primary deficit — taking in as much in taxes as it spends on things other than interest on its debt. But here’s the thing: Greece is currently running a huge primary deficit — 8.5 percent of GDP in 2009. So even a complete debt default wouldn’t save Greece from the necessity of savage fiscal austerity.

An astute blogger shoots back:

Mr. Krugman your world view is full of debt slavery.

Greece should leave the tyrannical European Union and then if it wishes can devalue their currency but not too much.

I respond:

Precisely correct on Krugman's worldview. When he utters "the necessity of savage fiscal austerity," you can almost imagine the fangs emerging from his dracula-like bloodlust. This is the type of mentality which is caused by the ideology of monetarism, i.e. the worship of money as an end unto itself. Thanks for being so forthright as to exhibit your true inner self Mr. Krugman. Bravo.

P.S.  The NY Slimes hasn't seen fit to post my remarks on the venereal pages. I can only take this to understand that I must have violated their abuse policy. Perhaps I was too hard on Count Dracula...

Greek Crisis

The Weimar style austerity regime being forced upon Greece is a harbinger of the agenda of the IMF regime for all so-called advanced nations. This is the financial pandemic that your friends at Goldman, et al are spreading around the globe.

More Enviro Crapola

"Germany's first offshore wind farm begins turning"

This, dear blog reader, is all a large load of manure. What is needed to power modern society is increasing energy density not diffuse wind power. That takes us backward several hundred years. (What would Don Quixote think of us fools?) As an astute commenter has already observed here, we have enough thorium for a thousand years. So why do we kowtow to at best misguided fools? Simply put:the agenda of radical environmentalism is to reduce the population. And there is big money behind this agenda. It doesn't take rocket science to see through the charade.

Goldman, Obama, Hedges, Pound of flesh

So let's see what is salient about Mr. Blankfein's testimony yesterday. First, I point to his fulsome adulation of Obama and his brand of  financial "reform." Maybe this explains why Obama was so heavily favored by Goldman's political contributions.  Of course, they were his top donor. (Even beating out George Soros.) But then Goldman always hedges their political bets in a thoroughly agile and timely manner, as the latest Wall Street psychobabble would put it. After all wasn't it Hank Paulson, he of Goldman stack who went on bended knee, hat in hand, crocodile tears and all to Pelosi and begged for a bailout? And Goldman got it too, didn't they? Straight from the Treasury to AIG to Goldman. Thanks Uncle Sam, you sucker! Of course, Blankfein says he would have got his pound of flesh anyway. Yes that's right. 200,000 teachers are being laid off now and Goldman, and the buggers on Wall St wallow in it. This simply is a noisome and odious disgrace and cancer upon the body politic which must be amended if we hope to ever truly prosper again.

Quantum Harmonic Oscillator Coherence Versus Quantum Random Fluctuations

If we submit ourselves to the mathematical description chosen by Heisenberg, et al, to represent so-called quantum processes, we are in essence submitting to a dogma of irrationality. The choice of  a matrix algebra of eigenstates based upon statistical probability is doubly unfortunate in this regard. Ah but the critic will respond that this choice of mathematics works. Actually, if one delves into the descriptive functions that are spliced in an ad hoc fashion time and time again in order to save the mathematical edifice from crumbling such as "operators" as an example, the fact is there is no necessity for embedding the fallacies of statistics and Grassmanian reductionism into the study of quantum physics. Rather, it is quite possible to envisage a wonderful coherence along the lines that Leibniz limns in his Monadology in the kind of superpositions that quantum systems evince. This, I believe, is quite the opposite to the gratuitous importing of the absurd into science which bled over into so much of the oeuvre of the "intellengentsia" during the twentieth century. Take Schopenhauer (please!) for instance.

Methinks the "Heritage Foundation" Doth Protest Too Much

Messer Robert Moffit of the Heritage Foundation (which name can only appropriately refer to the heritage of the likes of Benedict Arnold and Aaron Burr,) takes to the rather sallow pages of the Washington (Com)Post to assure us that Messer Obama is attempting to gull us (mon dieu!) into believing that "Obamacare" is after all only in their (Heritage's) tradition. I say-- what a dainty dish to put before us all. Lord a' mighty! Who is the pot and who the kettle here is a truly delicious conundrum, don't you think?

Spiral Paths from Atomic Phase Change to Black Hole Star Systems

Illustration from:

Field Ionization of Cold Atoms near the Wall of a Single Carbon Nanotube

Anne Goodsell, Trygve Ristroph, J. A. Golovchenko, and Lene Vestergaard Hau

I have maintained consistently for some time now the primacy of spiral orbitals along the surface of horn torii as a toy model for Riemannian metastable shockwave transformations through the singularity at its center. This toy model serves not only to adumbrate physical transformations, but also the historical impact of revolutionary ideas upon the functioning of society. The research illustrated above where a super cooled rubidium atom spirals toward a highly charged carbon nanowire and is subsequently stripped of an electron that tunnels into the tube while the resulting ion is repulsed is, I believe, an elegant demonstration of this principle.

Spirals occur as radiative processes move through spacetime. Imagine the orbit of the earth around the sun as the sun orbits the galaxy as the galaxy orbits its own group, etc. Embedded spirals. Here is an illustration of a spiral from a joint black hole star system whose anomalous physics is not well understood.

However, there are few attempts to model these radiative pathways as a field. Penrose's Twistor Theory is one such. However, his attempt to locate consciousness as a quantum effect is as misguided as Descartes' the pineal gland is the location of the soul. 

The Quixotic quest for a physical location of mind or soul is a result of a teleology or search for a final cause which is simply wrong. The assumption that that there is a frankly rather magical yet undiscovered physical explanation for human consciousness is due to a mode of thinking that assumes that substance is equivalent to mere physical sensation. This should have been abandoned once and for all after Leibniz devastatingly proved that the mind is of a different order that physical substance. That is, the mind is an indissoluble whole having no parts. It cannot be divided. Physical substance, meaning everything other than mind that may be conceived on the other hand may be divided. (The seeming paradox of individual quantum states, notwithstanding. For the condition of superposition shows that these states too are divisible via decoherence because of the very fact they exist as divisible quanta.) The mind in this sense participates as a kind of non-other to use Nicholas of Cusa's term. As Leibniz determined the mind is a sort of miniature creator reflecting the universal creative process of becoming. Or what is in Christian terms called Imago Viva Dei. The problem is that the materialists like Penrose can't stomach these truths, the which are not self evident, they are proven. 

Lowly Proteins Are Much Smarter Than Sir Isaac Newton

As is well known, (in some circles) the hoaxer Newton believed in magical pairwise action a distance instead of Kepler's principle of gravitation based upon elliptical functions. This mathematical fakery of predicting paths of points colliding and interacting with other points led later to disturbing  problems for the whole reductionist scheme known as the three body problem. Riemann addressed this dilemma in formal mathematics through developing a tool known as a multiply connected manifold. This article on protein research at Johns Hopkins further elucidates why in the biological substrate, biospherical processes are ordered very elegantly and lawfully not by pairwise interactions à la Newtonian quackery but instead by multi-modal/dimensional biological functions. Therefor providing more evidence, if any were needed that life even at its most elemental level, in this case proteins are much smarter than Newton was.

Hopkins researchers put proteins right where they want them

Location, location, location determines a protein's role

		IMAGE: Takanari Inoue, Ph.D. is a researcher at Johns Hopkins Medical Institutions. Click here for more information.

Using a method they developed to watch moment to moment as they move a molecule to precise sites inside live human cells, Johns Hopkins scientists are closer to understanding why and how a protein at one location may signal division and growth, and the same protein at another location, death.

Their research, published Feb. 14 inNature Methods, expands on a more limited method using a chemical tool to move proteins inside of cells to the periphery, a locale known as the plasma membrane.

"Where a particular protein is activated and the timing of that activation influence how a cell responds to outside stimulus," says Takanari Inoue, Ph.D., an assistant professor of cell biology at Johns Hopkins University School of Medicine. "Our goal with this newly expanded tool is to manipulate protein activities in many places in cells on a rapid timescale."

Cells cleverly have resolved the predicament of needing to respond to a near infinite array of external stimuli — temperature, for instance — even though they employ only a limited number of molecular players. The notion is that a single protein assumes multiple roles by changing its location or altering the speed and duration of activation.

Chemical signaling inside cells connects protein molecules through complex feedback loops and crosstalk, Inoue says, so knowing exactly how each protein contributes to which signals at what locations requires the ability to rapidly move proteins of interest to specific organelles found in cells. These include mitochondria (the power generators of cells) and Golgi bodies (the delivery systems of cells).

The Hopkins team chose the signaling protein Ras as the molecule it would attempt to send packing throughout a cell's interior. A regulator of cell growth that's often implicated in cancer, Ras has been long studied and it's known to be a molecular switch. However, no one has had the ability to discern what Ras does at different locations such as Golgi bodies and mitrochondria, much less what happens when Ras is activated simultaneously at any combination of these and other organelles.

Working with live human HeLa cells and Ras under a microscope, the team used a dimerization probe consisting of a special small molecule that simultaneously attracts two proteins that wouldn't normally have an affinity for each other and binds them together. In this system, one of the partner proteins is anchored to an organelle and the other is free floating inside the cell. Adding a chemical dimerizer induces the free protein to join the tethered one.

Using scissor-like enzymes, the team sliced and diced the DNA of the paired proteins to change the molecular address of its destination. They cut out the "mailing address" — known as a targeting sequence — that formerly delivered the protein unit to the plasma membrane and replaced it with new addresses (targeting sequences) that shipped it instead to specific organelles.

"We were able to manipulate protein activities in situ and very rapidly on each individual organelle," Inoue said. "Ultimately, this will help us to better understand protein function at these critical cellular components."

###

Unlimited Nuclear Fuel and Healthcare

So-called Progressives have been touting the Forster and Meadows "Limits  to Growth" screed for what seems like an eternity now. Remember, if you will --and if it doesn't make you heave--how the mawkish, grinning, and sweatered Jimmah Carter educated us dumb bunnies 'bout the "energy crisis?" Now, it just so happens that we have on this planet enough thorium resources for nuclear energy production to last at the current consumption rate for a thousand years. Now, of course, we are told that we have to cut back on "entitlements" by the usual suspects in the  Democratic and Republican parties' "think tanks." Why? Because of course, we have limited resources, don't you know. Our economy just can't support this inordinate spending on medical technology.  We can and we must bailout the too big to fail insane speculative schemers, on the other hand.Or so goes the Pete Peterson and his ilk's argument. Well, you can be a pessimistic sucker if you want. But just maybe you might want to be an optimistic human being. The choice is yours.

3D view of SuperNova

It almost seems as if the question in my previous blog called star gazing about what the universe looks like now all at once is partially being answered here. Thanks, Chandra, you almost read my mind.

Cassiopeia A: 3-D Model: A Star From the Inside Out

Subversion Masquerading as Science

Here is a somewhat lengthy quote from a National "Science" Foundation article that should convince anyone who is skeptical about the social engineering subversion of so-called climate science.

"FAIRFAX, Va., March 29, 2010—In a time when only a handful of TV news stations employ a dedicated science reporter, TV weathercasters may seem like the logical people to fill that role, and in many cases they do.

In the largest and most representative survey of television weathercasters to date, George Mason University’s Center for Climate Change Communication shows that two-thirds of weathercasters are interested in reporting on climate change, and many say they are already filling a role as an informal science educator.

“Our surveys of the public have shown that many Americans are looking to their local TV weathercaster for information about global warming,” says Edward Maibach, director of the Center for Climate Change Communication. “The findings of this latest survey show that TV weathercasters play—or can play—an important role as informal climate change educators.”  

According to the survey, climate change is already one of the most common science topics TV weathercasters discuss—most commonly at speaking events, but also at the beginning or end of their on-air segments, on blogs and web sites, on the radio and in newspaper columns.

Weathercasters also indicated that they are interested in personalizing the story for their local viewers—reporting on local stories such as potential flooding/drought, extreme heat events, air quality and crops. About one-quarter of respondents said they have already seen evidence of climate change in their local weather patterns.

“Only about 10 percent of TV stations have a dedicated specialist to cover these topics,” says University of Texas journalism professor Kristopher Wilson, a collaborator on the survey. “By default, and in many cases by choice, science stories become the domain of the only scientifically trained person in the newsroom—weathercasters.”

Many of the weathercasters said that having access to resources such as climate scientists to interview and high-quality graphics and animations to use on-air would increase their ability to educate the public about climate change.

However, despite their interest in reporting more on this issue, the majority of weathercasters (61 percent) feel there is a lot of disagreement among scientists about the issue of global warming. Though 54 percent indicated that global warming is happening, 25 percent indicated it isn’t, and 21 percent say they don’t know yet.

“A recent survey showed that more than 96 percent of leading climate scientists are convinced that global warming is real and that human activity is a significant cause of the warming,” says Maibach.  “Climate scientists may need to make their case directly to America’s weathercasters, because these two groups appear to have a very different understanding about the scientific consensus on climate change.”   

This survey is one part of a National Science Foundation-funded research project on meteorologists. Using this data, Maibach and his research team will next conduct a field test of 30-second, broadcast-quality educational segments that TV weathercasters can use in their daily broadcasts to educate viewers about the link between predicted (or current) extreme weather events in that media market and the changing global climate.

Ultimately, the team hopes to answer key research questions supporting efforts to activate TV meteorologists nationwide as an important source of informal science education about climate change."

More Information Theory Voodoo

Let us allow quackery unabashedly to speak for itself, thusly:

"At the heart of their idea is the tricky question of what happens to information when it enters a black hole. Physicists have puzzled over this for decades with little consensus. But one thing they agree on is Landauer's principle: that erasing a bit of quantum information always increases the entropy of the Universe by a certain small amount and requires a specific amount of energy.

Jae-Weon and co assume that this erasure process must occur at the black hole horizon. And if so, spacetime must organise itself in a way that maximises entropy at these horizons. In other words, it generates a gravity-like force."

Shakespeare's Magic

It's hardly surprising that one could entertain that Shakespeare was involved in the black arts, when so much of his overt subject matter is just that.   I.e., Midsummer's Night Dream, Prospero, etc. I have long maintained that Hamlet himself was a student of the black arts in Wurtemburg. Interesting that in Turgenev's speech, Hamlet and Don Quixote, he compares Hamlet to Faust. Anyway, I was just reading LaRouche's latest writing about Venice's takeover of Britain's monarchy via agents like Zorzi (aka Giorgi, whose Harmony of the Sphere's is parodied in Swift's isle of Laputa, as in the whorish false scientists) when I came across the issue of Cabbalism in the Merchant of Venice and the startling visual reference to that in the Globe theater. England at the time was overdosed with the occult. Robert Burton's depiction of the Rosicrucian's romp through jolly old England in his mystical book Anatomy of Melancholy gives a flavor of this. This continued unabated til the present, Isaac Newton's later alchemical magic wasn't a fluke. John Dee was at that time the real cabalistic 007head of British "intelligence," whose use of magic and drugs culminates today in the current British unleashing of the Crowleyan "Do what thou wilt" counterculture at her Satanic Majesty's request.

Globe theater and the Kabbala's Sephirot

You Can't Make This Kind of Crap Up

So it seems Obama's new appointee to head up Medicare/Medicaid Donald Berman has much in common with Sir Mick Jagger. (Please refer to blog below for more on this.) It is proudly proclaimed in his CV on his organization's website (given the Orwellian misnomer of the Institute for Healthcare Improvement): "In 2005, he was appointed “Honorary Knight Commander of the British Empire” by the Queen of England in honor of his work with the British National Health Service." How very N.I.C.E. -- as exampled in the following reportage:

"Cancer Groups to Appeal against NICE’s Decision to Rule out Use of Vidaza

The Cancer groups are going to appeal against a declaration made by the National Institute for Health and Clinical Excellence, which will deny the NHS patients in England and Wales an access to a drug called Vidaza, which is used for the treatment of bone marrow diseases.(...)"

and

"Tens of thousands of NHS workers could be sacked and thousands of hospital beds lost under plans outlined by strategic health authorities, it was reported.

The plans could also see procedures such as hip replacements scrapped and patients encouraged to email doctors rather than visit surgeries, according to the Daily Telegraph.

Proposals were drawn up by the 10 English strategic health authorities for productivity and efficiency savings.

The plans come after NHS chief executive Sir David Nicholson spoke of the need to make between £15 and £20 billion in productivity efficiency savings over three years. The Department of Health said it was "committed to protecting the NHS frontline". But the Telegraph has seen documents from SHAs which show how the cuts could fall on hospital services."

A Proclamation of a New Dark Age?

"Across the globe today people will be turning off all their lights for an hour starting at 8:30pm local time tonight for the World Wildlife Fund's annual Earth Hour campaign."

Right on cue, like some modern day Zeus, the Worldwide Fund for Nature, more commonly known as the British monarchy, has issued this démarche to their loyal subjects: Let there Be Darkness. Is it any wonder that Mick Jagger was knighted by what he too truly proclaimed to be Her Royal Satanic Majesty?

Frozen in Time

Did you know dear reader that there is living in our world a 17 year old girl who is still developmentally an eleven month old infant! She has never aged past infancy and seems frozen in time, it is amazing that this is not a tremendous cause célèbre. Although, on second thought, most of what passes for successful celebrity these days is the most banal nonsense imaginable. 


What if our media were focused upon bringing before our populace questions of signal import like unraveling whether there exists an underlying regulator of biological development? This would surely promote the general welfare, don't you think?

"A case study of "disorganized development" and its possible relevance to genetic determinants of aging

Walker, Richard F.; Pakula, Lawrence C.; Sutcliffe, Maxine J.; Kruk, Patricia A.; Graakjaer, Jesper; Shay, Jerry W.

Mechanisms of Ageing and Development (2009), 130(5), 350-356 CODEN: MAGDA3; ISSN: 0047-6374. English.

In 1932, Bidder postulated that senescence results from "continued action of a (genetic) regulator (of development) after growth ceases (maturation occurs). " A 16-yr-old girl who phys. appears to be an infant has not been diagnosed with any known genetic syndrome or chromosomal abnormality. The subject's anthropometric measurements are that of an 11-mo-old. Coordinated development of structures for swallowing/breathing has not occurred resulting in dysfunctional digestive and respiratory systems. Brain structure, proprioception and neuroendocrine functions are infantile. Dental and bone ages are pre-teen, while telomere length and telomerase inactivity suggest a cellular age at least comparable to her chronol. age. Sub-telomeric microdeletions known to be responsible for developmental delay and chromosomal imbalances are not present. Findings suggest that the subject suffers from "developmental disorganization" resulting from spontaneous mutation of Bidder's putative "regulator" of development, thereby providing an opportunity to locate and identify developmental gene(s) responsible for ensuring integrated and coordinated change in form and function from conception to adulthood. If their continued expression beyond maturation erodes internal order to promote senescence then further study of her DNA and testing of homologous genes in animal models may provide clues to genetic determinants of aging and human life span."

The Ironic Universe: updated

"Distant galaxy clusters mysteriously stream at a million miles per hour along a path roughly centered on the southern constellations Centaurus and Hydra. A new study led by Alexander Kashlinsky at NASA's Goddard Space Flight Center in Greenbelt, Md., tracks this collective motion -- dubbed the "dark flow" -- to twice the distance originally reported."

This dark flow motion together with cosmological electromagnetic anisotropy (or birefringent polarization) together seem to point to some sort of directed universal evolution of even supposed inorganic matter that no sanitized purely mathematical model can account for. It is evidence that no matter how long one attempts to achieve a so-called unified field theory the universe will always present us with some unexpected singularities due to its continuing evolution. We will forever be baffled by the fact that the universe always seems to surprise us.

Here's yet another irony in the news:

"Sunspots are supposedly rooted to the bottom of the belt," says Hathaway. "So the motion of sunspots tells us how fast the belt is moving down there."

He's done that—plotted sunspot speeds vs. time since 1996—and the results don't make sense. "While the top of the conveyor belt has been moving at record-high speed, the bottom seems to be moving at record-low speed. Another contradiction."

Could it be that sunspots are not rooted to the bottom of the Conveyor Belt, after all? "That's one possibility" he notes. "Sunspots could be moving because of dynamo waves or some other phenomenon not directly linked to the belt."


March, 2017:

Running away from Einstein

"This 10 million light year-wide ring made up of small galaxies is expanding rapidly like a mini Big Bang. The team believe our neighbouring galaxy, Andromeda, once flew past our own galaxy at close range, creating a sling-shot of several small galaxies.

Dr Hongsheng Zhao, Reader in the School of Physics and Astronomy and co-author of the paper, published in Monthly Notices of the Royal Astronomical Society by Oxford University Press, said: "If Einstein's gravity were correct, our galaxy would never come close enough to Andromeda to scatter anything that fast.""


November, 2019

"Scientists are finding that galaxies can move with each other across huge distances, and against the predictions of basic cosmological models. The reason why could change everything we think we know about the universe."

April, 2020

The fine structure constant has a directional anisotropy.

"And it seems to be supporting this idea that there could be a directionality in the universe, which is very weird indeed," Professor Webb says.

"So the universe may not be isotropic in its laws of physics - one that is the same, statistically, in all directions. But in fact, there could be some direction or preferred direction in the universe where the laws of physics change, but not in the perpendicular direction. In other words, the universe in some sense, has a dipole structure to it.

"In one particular direction, we can look back 12 billion light years and measure electromagnetism when the universe was very young. Putting all the data together, electromagnetism seems to gradually increase the further we look, while towards the opposite direction, it gradually decreases. In other directions in the cosmos, the fine structure constant remains just that - constant. These new very distant measurements have pushed our observations further than has ever been reached before."


June, 2020

K-State study reveals asymmetry in spin directions of galaxies

The patterns span over more than 4 billion light-years, but the asymmetry in that range is not uniform. The study found that the asymmetry gets higher when the galaxies are more distant from Earth, which shows that the early universe was more consistent and less chaotic than the current universe.

But the patterns do not just show that the universe is not symmetric, but also that the asymmetry changes in different parts of the universe, and the differences exhibit a unique pattern of multipoles.

"If the universe has an axis, it is not a simple single axis like a merry-go-round," Shamir said. "It is a complex alignment of multiple axes that also have a certain drift."

September, 2020

Why is there a normal galaxy sitting at the edge of the universe?

"Massive stars blow powerful winds, supernovae detonate like flashbulbs, and all that energy released should stir the gas up in the galaxy, making it irregularly shaped (plus, that early in the age of the Universe there just hadn't been a lot of time to get organized). Most distant galaxies we see are indeed blobby. The fact that this galaxy has a disk that appears to be pretty calm and stable is bizarre."

"Interestingly, it’s not alone. Earlier in 2020 astronomers announced they found a disk galaxy at about the same distance, called the Wolfe Galaxy. Like this one, it’s not understood how it can exist. Clearly, the theoretical models are wrong, or at least (and more likely) incomplete. Obviously, there’s more to learn about galaxies that exist at the edge of the observable Universe."

November, 2020

Scientists Detect Hints of Strange New Physics in The Universe's Background Radiation


"As far as we have been able to measure so far, there's only one fundamental interaction that breaks parity symmetry; that's the weak interaction between subatomic particles that is responsible for radioactive decay. But finding another place where parity symmetry breaks down could potentially lead us to new physics beyond the Standard Model."

"And two physicists - Yuto Minami of the High Energy Accelerator Research Organisation in Japan; and Eiichiro Komatsu of the Max Planck Institute for Astrophysics in Germany and Kavli Institute for the Physics and Mathematics of the Universe in Japan - believe they have found hints of it in the polarisation angle of the CMB."

December 2020

Are primordial magnetic field theories getting in a twist?

"In cosmic voids where the density of galaxies is far lower than standard, astronomers have observed weak magnetic fields that may provide a window into the early universe. The fields 10-17-10-10 G in magnitude with large coherence lengths of up to megaparsecs are thought to have their origins in the early universe, but so far it is unclear when or how they were generated."

December 2020

Portrait of young galaxy throws theory of galaxy formation on its head

"Scientists have challenged our current understanding of how galaxies form by unveiling pictures of a young galaxy in the early life of the Universe which appears surprisingly mature.

The galaxy, dubbed ALESS 073.1, appears to have all of the features expected of a much more mature galaxy and has led the team of scientists to question how it grew so fast."

February 2021

Discovery of a Giant Arc in distant space adds to challenges to basic assumptions about the Universe

"The Giant Arc, which is approximately 1/15th the radius of the observable universe, shows as an enormous, nearly symmetrical, crescent of galaxies in the remote Universe. It is twice the size of the striking Sloan Great Wall of galaxies and clusters that is seen in the nearby Universe. This new discovery of the Giant Arc adds to an accumulating set of (cautious) challenges to the Cosmological Principle."

June 2021

Discovery of ASKAP J173608.2−321635 as a Highly-Polarized Transient Point Source with theAustralian SKA Pathfinder 

"We report the discovery of a highly-polarized, highly-variable, steep-spectrum radio source, ASKAP J173608.2−321635, located ∼4 ◦ from the Galactic center in the Galactic plane. (...)  We discuss possible identifications for ASKAP J173608.2−321635 including a low-mass star/substellar object with Corresponding author: Ziteng Wang zwan4817@uni.sydney.edu.au, tara.murphy@sydney.edu.au arXiv:2109.00652v1 [astro-ph.HE] 2 Sep 2021 2 Wang et al. extremely low infrared luminosity, a pulsar with scatter-broadened pulses, a transient magnetar, or a Galactic Center Radio Transient: none of these fully explains the observations, which suggests that ASKAP J173608.2−321635 may represent part of a new class of objects being discovered through radio imaging surveys. "

September 2021

Early Massive Galaxies ran out of gas, Shutting Down Their Star Formation

"But what is removing the cold gas from the galaxies? Astronomers are stumped, and will have to continue their observations to find clues to this great galactic mystery. “We still have so much to learn about why the most massive galaxies formed so early in the Universe and why they shut down their star formation when so much cold gas was readily available to them,” said Whitaker. “The mere fact that these massive beasts of the cosmos formed 100 billion stars within about a billion years and then suddenly shut down their star formation is a mystery we would all love to solve, and REQUIEM has provided the first clue.”"

October 2021

Strange radio waves emerge from direction of the galactic centre

"Astronomers have discovered unusual signals coming from the direction of the Milky Way’s centre. The radio waves fit no currently understood pattern of variable radio source and could suggest a new class of stellar object.

“The strangest property of this new signal is that it is has a very high polarisation. This means its light oscillates in only one direction, but that direction rotates with time,” said Ziteng Wang, lead author of the new study and a PhD student in the School of Physics at the University of Sydney.

“The brightness of the object also varies dramatically, by a factor of 100, and the signal switches on and off apparently at random. We’ve never seen anything like it.”"

March 2022

Mysterious, Swirling Waves Discovered in the Sun – Incredible Speed Defies Explanation

"Researchers from NYU Abu Dhabi’s (NYUAD) Center for Space Science have discovered a new set of waves in the Sun that, unexpectedly, appear to travel much faster than predicted by theory.

"In the study, Discovery of high-frequency-retrograde vorticity waves in the Sun, published in the journal Nature Astronomy, the researchers — led by Research Associate Chris S. Hanson — detailed how they analyzed 25 years of space and ground-based data to detect these waves. The high-frequency retrograde (HFR) waves — which move in the opposite direction of the Sun’s rotation — appear as a pattern of vortices (swirling motions) on the surface of the Sun and move at three times the speed established by current theory.

"Complex interactions between other well known waves and magnetism, gravity, or convection could drive the HFR waves at this speed. “If the HFR waves could be attributed to any of these three processes, then the finding would have answered some open questions we still have about the Sun,” said Hanson. “However, these new waves don’t appear to be a result of these processes, and that’s exciting because it leads to a whole new set of questions.”"

December 2022

Tetrahedral Asymmetry Handedness in Galactic Distributions

https://arxiv.org/abs/2206.04227

February 2023

"This is our first glimpse back this far, so it's important that we keep an open mind about what we are seeing," Leja said. "While the data indicates they are likely galaxies, I think there is a real possibility that a few of these objects turn out to be obscured supermassive black holes. Regardless, the amount of mass we discovered means that the known mass in stars at this period of our universe is up to 100 times greater than we had previously thought. Even if we cut the sample in half, this is still an astounding change."

Discovery of massive early galaxies defies prior understanding of the universe

January 2024

The Big Ring galaxy cluster discovery challenges the principle that the universe is smooth at cosmological scales.

https://www.bbc.com/news/science-environment-67950749

Time and Light

Einstein's principle of the invariant speed of light no matter what the relative motion is from the physical starting point from which that light emanates, indicates that time itself must be relative to this universally inherent quality of boundedness. The function of light, more broadly conceived as propagation of electromagnetic wave phenomena, varies relative to the type of bounding sphere (geosphere, biosphere, noosphere) as defined by Vernadsky, upon which it operates.

First, what Vernadsky labelled the geosphere or the inorganic realm is the result of the creation of elements up to iron by nuclear fusion in the furnaces of stars and heavier elements by shockwave explosions in supernovae (or perhaps other hitherto undiscovered inorganic processes.) The scale of time for the evolution of elements is only bounded by the age of the universe itself. In Riemann's philosophical notes we find musings upon the hierarchical relativity of time. He takes as his model Fechner's works on the Zend-Avesta. Fechner views the systems of stars as a higher form of a universal life principle. Vernadsky dismisses this as pantheism, or a form of world soul, purporting  to bestow consciousness upon the inorganic. However, I am more charitable toward Fechner's scheme. It is the case that inherent in the formation of planets from stars, the elements essential to life, and cosmic energy is embedded a principle of life. The question of whether this universal order is higher because it encompasses all of time and thereby all possibilities, or lower because it is merely inorganic dissolves when viewed from the standpoint of how technology may use the principle of fusion, matter anti-matter reactions, and other as yet undiscovered sources of energy/matter transformations. Seen from this perspective,that which Vernadsky denominates as the Noosphere, humanity noetically continues or recapitulates the process of creation in the sense that Nicholas of  Cusa gives as the Microcosm recapitulating the entire development of the Macrocosm.

Second, the photosynthetic property of light on the biosphere is the obvious transformation that leads to large scale evolutionary dynamics. We also now find that life thrives at the cellular level as thermophiles and extremophiles feeding from thermal and radioactive  radiation. For the biosphere, the addition of a directional sort of causality that involves a primitive sort of choice is manifest. The opposite chirality of the amino acid and sugar molecules evince this. It is quite remarkable that the ATPase mitochondrial motor that produces usable biological energy rotates either clockwise or counter  clockwise depending on whether the form of life is aerobic or anaerobic. Further, an ongoing quality of directness inheres in the evolutionary development of life forms that are able to capture and efficiently use more energy dense sources of nourishment. Thus, for Vernadsky, the biosphere is bounded by this evolutionary principle.

Third, the human creative interaction with light and radiative processes more generally, via technology shows itself in a multi-functional evolutionary way. At the dawning of civilization, epic poetry underlines the discovery  of fire from wood burning. This is the first in a succession of advancements in fuel sources that lift humanity's inventors into the role of self conscious directed evolution benefiting  unborn future generations. Just as fundamental to these epic poems is the invention of navigation via decoding the positions and movements of the light from stars. As LaRouche has shown, within any one mode of technology, there is posed a crisis for society through the using up of the relatively limited energetic resource. This is the principle which by necessity bounds the proper functioning of the Vernadsky's Noosphere. Here for humanity, creativity and choice becomes a moral imperative for ensuring that we bestow on our posterity the capability to advance understanding and application of light understood literally and metaphorically. This power of continuous creation we can either willfully promote or deny. If we insanely and suicidaly insist upon the primacy of the obligation to pay debt which has been manufactured by the machinations of the global monetarist oligarchy then we will have willfully doused this light. And a dark age will have justly be brought down upon us. On the other hand, if we defeat this monetarist cabal and their control, we can look to the future prospect of our species happiness through virtually limitless colonization of space.

Time as a Vector of Biophysical Relativity

"In the far northern reaches of the Arctic, day versus night often doesn't mean a whole lot. During parts of the year, the sun does not set; at other times, it's just the opposite. A new study reported online on March 11th in Current Biology shows that Arctic reindeer have come up with a solution to living under those extreme conditions: They've abandoned use of the internal clock that drives the daily biological rhythms in other organisms."

In our human world, we adopt the principle of time as the counting of cycles and the counting of things as equivalent in an unconscious act. We don't stop to question whether the process is truthful with respect to the world around us because it is self evidently so. We have embedded within our biological brain a suprachiasmatic nucleus that operates as an internal 24 hour clock.  As the above research indicates, this clock may be biologically overridden in the circumstance that it is out of sync with the earth's own internal diurnal clock of alternation of day and night.

Why Any "Formula for Success" Must Inevitably Fail

Kepler castigated the purveyors of algebra as standing in the way of his revolutionary rewriting the laws of what is today called astrophysics. Applying Keplar's principled objection to algebra to the frame of reference of society's functioning at large is urgently necessary if we are to survive and progress. For what is an algebra when it comes to society except the tissue of accepted rules of behavior, whether those rules be conscious or not? And how does it happen that a society dooms itself to a dark age? Isn't it because it is incapable of the sort of change in its way of doing things necessary for its survival? Up to this point in my argument, a radical environmentalist advocating "change" might nod his or her head in agreement. Aren't they for radical change? Actually, the truth is just the opposite. They are the most bitter inalterable haters of true change. They romanticize the "noble savage." Like the transcendentalists of yore. Like Carlos Castaneda they profess love of soil (and often psychedelics, which should be more accurately labeled psychotomimetics.) It should be quite simple to see that this is in essence proto-fascist whether or not it is labeled as leftism. Except that most among us are chained to our way of doing and thinking about things.

Isn't it the case that the universe has a built in principle of evolutionary change? If there is a crisis in remaining fixed in our way of doing things, isn't there always a potential solution available? In fact isn't it a type solution that leads to more freedom for humanity? If even a class of diseases shows the potential for indefinite change in morphology such that their macrophage combatants exhibit this infinite evolvability, how much more so the mental capacity to evolve society? Tis is what Leibniz meant by the preordained harmony of the best of all possible worlds. Contrary to that false portrayal by that wretch Voltaire, not that there was no inevitable painful crises to be overcome by society through application of scientific progress. 


Today's economic crises are based upon a cabal of financiers setting the rules to save their insane game of speculative looting of the world's population. To save the bubble of debt that they have manufactured out of thin air, inevitably they must demand increasing the death rate. This is the ugly truth behind their political, media and academic hod carriers clarion calls for "entitlement reform." This is why they turn apoplectic and shout the label of "extremism" at any who thus accurately expose their game. The only way out of the crisis is to do the unthinkable: break the algebraic rules of the game. Write off the lunatic forms of derivative securities. Set up agreements among nations above the so called markets that will assure lasting referred investments in infrastructure, energy intensive agriculture and industry.

Johannes Kepler

Today's Dark Age Flagellants

"A seven-month old baby girl survived a shot to the chest after her parents shot themselves and their two-year-old in a global warming murder-suicide pact."

The masquerade of pseudo-science is increasingly wearing thin.  Hatred against technology deployed for preservation of the Ancien Regime is the puppeteer's sport. Drive them mad and reap the profit of death is their emblem. Thus the flagellants spread the plague with the hue and cry that humanity is only fit for evil. Who benefits from this?

Star Gazing

We map the universe by looking through the past as light travels to our neighborhood. But the interesting question is, given what we know of likely scenarios of its potential evolvability, what does the map of the known universe in its entirety look like in the here and now? Because perhaps approaching the issue in this way may lead to thinking of universal structural and functional interrelatedness in new and useful ways.

Political Skulduggery

In the bowels of Dante Alighieri's Inferno, Count Ugolino, the traitor, gnaws upon the skull of the corpse of his former political ally Ruggieri. Isn't this an apt metaphor for both today's Democratic and Republican parties currying the favor of high finance to impose brutal austerity to collect debt. But which party is the better at it? Of course, "debts must be paid by someone," intones the devil. Who will perform the best as his beloved minion? He or she will have the honor to reside there in the pit of hell next to Satan. Gnawing away for eternity...

Global Warming.Cui Bono?

Mathusianism. Whence comes it? An oligarchical hatred of humanity. Prince Phillip's stated desire, for example, that he would like to be reincarnated as a deadly virus to reduce the world's population. This hatred persists over millennia. It is old as mud. It is the hatred of the pagan would-be gods for discoveries that lift humanity out of the muck and mire. Thus the myth of Zeus' torture of Prometheus the bringer of fire.

More Goldman Sachs Bedtime Stories

Today's NY Times reports that Goldman did everything in its power to bring down the mortgage backed derivative securities market to put the squeeze on AIG to pay off its gamble that the mortgage valuations would collapse. Of course, anyone not drunk on the hype that mortgage values never collapse, foresaw that exactly what Goldman bet on was in fact inevitable.

Therefore the contents of this article completely gives the lie to the oft repeated line by a supine media "that no one could have known that the markets would crash." In actual fact, Goldman not only knew but did everything to make that happen, including inducing its partner in crime Paulson to grovel for more loot, on bended knee, crocodile tears and all, before a scarified congress. What a sordid, shameful con game these "honorable men" have foisted upon us rubes.

Jail All The Bankers First!

"Goldman Sachs Group Inc., trying to show it is responsive to public pressure over its pay, said Chairman and Chief Executive Lloyd Blankfein would get a $9 million bonus for 2009, a fraction of the $68.5 million payout he got in 2007."

The discriminating reader will, of course, be amused by this foregoing sentence. In actual fact, it were meet that Messer Blankfein find himself in the hoosegow, alongside his brethren in crime Messers Paulson, Geithner, and Summers. Surely, John Dillinger and Baby Faced Nelson are rolling over in their graves with envy at Mr Blankfein's hubris.

(A thousand pardons dear reader. I foolishly left off Messer Bernanke from my list.)

Is the World's Oldest Profession Economics?

From today's headlines:

Economy Sheds 20,000 Jobs But Rate Drops to 9.7 Percent

While a sharp increase in the number of people giving up looking for work helped to depress the jobless rate, some details of the employment report were encouraging. The number of "discouraged job seekers" rose to 1.1 million in January from 734,000 a year ago.

Hmm. Very interesting. Shouldn't we encourage the Labor Department for the sake of full disclosure to label these "discouraged workers" as "desaparecidos" a la Argentina or perhaps they might prefer the Stalinist "Damnatio Memoriae" method of photographic erasure. I guess the statisticians will do anything to provide the illusion that there is a "recovery" even though the corpse of the economy rots apace.

The Current Essential Difference Between Democrats and Republicans

In order to adduce the distinction between the Democratic and Republican parties in the United States today, first one must recognize that the only appropriate arena within which to make an unbiased judgment, ab initio, is the province of animal psychology.
The careful reader may object that I have heretofore shown only disdain for any claim that behaviorism is to be accorded the label of the science of the human psychology. This is indeed quite true. No such strictures imposed by a supposed science that limits the scope of humanity's capacity to a fixed set of behavioral patterns could ever account for the creative problem solving evinced in our species' nature time and again. Therefore behaviorism deserves only opprobrium. However, in this instance, you must bear in mind that we are dealing with the degeneration of humanity into these bestial parties which adamantly refuse to partake of precisely that truly unique human quality of problem solving.
Moreover, it is the characteristic behavior of that particular animal from time immemorial referred to as man's best friend with which we must compare the subjects of our inquiry. Every dog has its day. One party is up now, only to be toppled by a disgruntled and betrayed populace. They both serve the interests of their lords in their own way though. They serve as shills like the proverbial dog and pony show keeping one's attention on the circus while one's pocket is picked. This is all the current debate about budget cutting signifies. Nothing more. The Democratic dogs and Republican dogs snarl and yelp, meanwhile ladies and gentleman our future is being stolen by the pickpockets of the financiers that control the show from beginning to end.

What Leibniz Did Not Imply

When Leibniz wrote that music is the pleasure the mind derives from counting without being aware of the act of counting, he foreshadowed the continuous development of music up to the summit of Beethoven's late string quartets. However, he would sorely disapprove of any aesthetics that would try to impose counting or any of its mathematical extensions as the essence of what he called the pleasure of the mind. This is what Beethoven himself so publicly parodied in that vulgar mechanician Maelzel. This is what Furtwaengler execrated in the conducting of Tuscanini. And it is where Goethe went off the rails in his theory of color.Likewise in Felix Klein's dubious study of curvature and statuary.

"Why the mirror lies: Individuals with body dysmorphic disorder see their own faces differently "

Conversely, according to Leonardo da Vinci from his notebook writings, the opposite can be true. That is, that one's notion of facial beauty may be unduly influenced by narcissism. However, Hieronymous Bosch appears to have had a variation of this problem. He has been reported to have uttered that he only let his children out at night because they were so ugly.

Headlines We'd Like to See

JFK 1962: "We shall go to the moon." Obama 2010: "We shall not go to the moon. (We shall go to hell, however.)"

"Fish Oil May Prevent Psychosis"

Then I say this--force feed cod liver oil to all our representatives and the media--NOW!

Idea for New Direction for Obama

Use the MASH theme song from now on: "Suicide is painless-- it brings on many changes"