Much brouhaha has been ginned up as of late regarding the President's youthful embrace of marijuana and cocaine. Many who clamor for pot legislation are raising the hue and cry of calling him hypocrite. But taking into consideration that Obama's number goal is his extremely narcissistic financial aggrandizement, this is no surprise. I am all but certain if he perceived that there would be a big payback for him, he would be all over legalization. (As was the case in his recent epiphany on gay marriage.)
Besides which, his Justice Department is doing their utmost to put a lid on the HSBC (Hong Kong Shanghai Bank Corporation) multi-billion dollar dope money laundering situation. And then there is the stonewalling on the ATF gun giveaway program.
To further prove my point now Obama is having our government be the guarantor of the insane practice of derivatives trading.
Eratosthenes first measured the circumference of the earth from the shadows cast by the sun. Today, humanity's fitness to survive will be measured by our ability to conquer that same thermonuclear fusion that casts those shadows. Thus, Prometheus will truly be unbound.
Monday, May 28, 2012
Saturday, May 26, 2012
Christine Lagarde: The Face of Evil
A practically unspeakable horror of opprobrium has just been emitted Sibyllike from the orifice of the new head, Christine Lagarde, of the International Monetary Fund (which a deceased quondam associate of mine Hulan Jack with good reason called the International Murder Fund.) At the same instant that Greek pensioners are committing suicide in protest over the grinding austerity imposed upon them, and worse yet, the pharmacies there are running out of life saving medicines, Ms. Lagarde pronounces that it is time to pay the piper and that she cares more about dying Africans than dying Greeks. This, after IMF conditionalities for decades have imposed untold immiseration and a hecatomb of death upon those very same Africans Ms. Lagarde sheds copious crocodile tears for now. If anyone hearing this is not repulsed by this overt admission of pure evil, then they have no heart nor mind.
Lately, I have learned that an ancestor of mine was jailed in a town near Salem during the witch trial hysteria as a "mischief maker." It was indeed a black mark upon that most noble of experiments in the Massachussets Bay Charter that Franklin later picked up from Cotton Mather as the basis for the so called establishment clause in our Constitution, the principle of doing good for future generations. However, if ever there were a real life witch in our midst conjuring up poisonous potions to be served to hapless victims it is this soulless woman.
Fredrich Schiller once wrote that Shakespeare's Iago (like Beethoven's Pizarro in his opera Fidelio) was too much a one sided character purely evil and capable of no development to be fit for a dramatic portrayal. But, like her predecessors Hitler or Napoleon, Ms. Lagarde proves that such irredeemable characters are all too real.
Lately, I have learned that an ancestor of mine was jailed in a town near Salem during the witch trial hysteria as a "mischief maker." It was indeed a black mark upon that most noble of experiments in the Massachussets Bay Charter that Franklin later picked up from Cotton Mather as the basis for the so called establishment clause in our Constitution, the principle of doing good for future generations. However, if ever there were a real life witch in our midst conjuring up poisonous potions to be served to hapless victims it is this soulless woman.
Fredrich Schiller once wrote that Shakespeare's Iago (like Beethoven's Pizarro in his opera Fidelio) was too much a one sided character purely evil and capable of no development to be fit for a dramatic portrayal. But, like her predecessors Hitler or Napoleon, Ms. Lagarde proves that such irredeemable characters are all too real.
Wednesday, May 23, 2012
Every Time a Light Goes Off New Brain Cells Are Being Born
The culminating proof of an hypothesis that was proffered by what Bernhard Riemann denominated "geistesmassen" or loosely "thought-masses" some 150 years ago is to be applauded. Researchers at the Pasteur Institute have demonstrated that neurogenesis in mice correlates with learning and memory. This has been for readers of these pages been a recurring theme from the first.
But here I want to pause for a moment to reflect on why with what would see to be no empirical evidence Riemann could have foretold this astounding development. The effort to locate some intimate connection between the "soul" and the material goes back to the earliest of thinkers. Leibniz who successfully refuted Descartes' formula for force, posited an harmonic principle of continuous development among differential degrees of substance in his great work the Monadology.
It was a major setback for humanity that Leibniz' bid to become prime minister of England was put down by the Cabal of practitioners of the black arts promoting the crazed Isaac Newton's useless mathematical scribblings. It is to be rued that this anti German prejudice continued to be fueled in the nascent American republic. For example, it was considered slander to label Poe's writings "Germanic." The fact that Schiller's ideas of aesthetics were instrumental in ousting that meglomaniac Napoleon notwithstanding...
But the genius of Franklin's Constitution that hearkens back to Cusa's Universal Concordance principles knows no boundaries religious or dogmatic. And it is the establishment of a government of, by, and for the wise that promotes the improvements in physical wealth that correlates with scientific breakthroughs, that provides the proof of the same principle discovery of the function of neurogenesis writ large. So, it is only lawful that there is a concrete parallelism in the realm of the small, even within the brain of a mouse! For as Leibniz would have it, we are not a blank slate thrown into this world as empty potter's vessels, but rather the willful microcosm of unfolding universal harmonic and continuing development best exemplified most immediately in the Grosse Fugue of Beethoven.
But here I want to pause for a moment to reflect on why with what would see to be no empirical evidence Riemann could have foretold this astounding development. The effort to locate some intimate connection between the "soul" and the material goes back to the earliest of thinkers. Leibniz who successfully refuted Descartes' formula for force, posited an harmonic principle of continuous development among differential degrees of substance in his great work the Monadology.
It was a major setback for humanity that Leibniz' bid to become prime minister of England was put down by the Cabal of practitioners of the black arts promoting the crazed Isaac Newton's useless mathematical scribblings. It is to be rued that this anti German prejudice continued to be fueled in the nascent American republic. For example, it was considered slander to label Poe's writings "Germanic." The fact that Schiller's ideas of aesthetics were instrumental in ousting that meglomaniac Napoleon notwithstanding...
But the genius of Franklin's Constitution that hearkens back to Cusa's Universal Concordance principles knows no boundaries religious or dogmatic. And it is the establishment of a government of, by, and for the wise that promotes the improvements in physical wealth that correlates with scientific breakthroughs, that provides the proof of the same principle discovery of the function of neurogenesis writ large. So, it is only lawful that there is a concrete parallelism in the realm of the small, even within the brain of a mouse! For as Leibniz would have it, we are not a blank slate thrown into this world as empty potter's vessels, but rather the willful microcosm of unfolding universal harmonic and continuing development best exemplified most immediately in the Grosse Fugue of Beethoven.
Monday, May 14, 2012
More Forgotten Lore--Masonic Magic, Mormons and The Raven
Last summer my father mentioned that two of my forbears (great great grandfathers, I think) were somehow involved, one as a judge and the other a state legislator, in the trial of the masons for the murder of William Morgan. This was the fellow who wrote a book exposing that the initiation into masonry included an oath that if you divulged their secrets or became disloyal you would have your tongue ripped out and be buried alive at sea. John Quincy Adams played a pivotal role in the anti masonic upsurge shortly thereafter. It is interesting that Adams was associated in publishing with one of my ancestor's literary circle Joseph Dennie.
Now it just so happens that the widow of William Morgan became one of the wives of Joseph Smith the founder of the Mormons. Now this same Smith was very deeply into what he called true and perfect masonry. He even possessed a magic amulet called the Jupiter Table. Isaac Newton was fanatically consumed in the alchemical "study" of the traditional Hermes Trismegistus' Emerald Table. (I think therefore Newton's mind might be proof of a true Tabula Rasa, in my humble opinion.)
Here is a poem exalting Hermes Trismegistus from Edgar Poe's adversary H.W. Longfellow:
"Was he one or many, merging
Name and fame in one,
Like a stream, to which, converging,
Many streamlets run ?
Who shall call his dream fallacious ?
Who has searched or sought
All the unexplored and spacious
Universe of thought ?
Who in his own skill confiding,
Shall with rule and line
Mark the border-land dividing
Human and divine ?
Trismegistus ! Three times greatest !
How thy name sublime
Has descended to this latest
Progeny to time !"
The Raven by Edgar Allan Poe
Once upon a midnight dreary, while I pondered, weak and weary,
Over many a quaint and curious volume of forgotten lore,
While I nodded, nearly napping, suddenly there came a tapping,
As of some one gently rapping, rapping at my chamber door.
"'Tis some visitor," I muttered, "tapping at my chamber door -
Only this, and nothing more."
Ah, distinctly I remember it was in the bleak December,
And each separate dying ember wrought its ghost upon the floor.
Eagerly I wished the morrow; - vainly I had sought to borrow
From my books surcease of sorrow - sorrow for the lost Lenore -
For the rare and radiant maiden whom the angels name Lenore -
Nameless here for evermore.
And the silken sad uncertain rustling of each purple curtain
Thrilled me - filled me with fantastic terrors never felt before;
So that now, to still the beating of my heart, I stood repeating,
"'Tis some visitor entreating entrance at my chamber door -
Some late visitor entreating entrance at my chamber door; -
This it is, and nothing more."
Presently my soul grew stronger; hesitating then no longer,
"Sir," said I, "or Madam, truly your forgiveness I implore;
But the fact is I was napping, and so gently you came rapping,
And so faintly you came tapping, tapping at my chamber door,
That I scarce was sure I heard you"- here I opened wide the door; -
Darkness there, and nothing more.
Deep into that darkness peering, long I stood there wondering, fearing,
Doubting, dreaming dreams no mortals ever dared to dream before;
But the silence was unbroken, and the stillness gave no token,
And the only word there spoken was the whispered word, "Lenore?"
This I whispered, and an echo murmured back the word, "Lenore!" -
Merely this, and nothing more.
Back into the chamber turning, all my soul within me burning,
Soon again I heard a tapping somewhat louder than before.
"Surely," said I, "surely that is something at my window lattice:
Let me see, then, what thereat is, and this mystery explore -
Let my heart be still a moment and this mystery explore; -
'Tis the wind and nothing more."
Open here I flung the shutter, when, with many a flirt and flutter,
In there stepped a stately raven of the saintly days of yore;
Not the least obeisance made he; not a minute stopped or stayed he;
But, with mien of lord or lady, perched above my chamber door -
Perched upon a bust of Pallas just above my chamber door -
Perched, and sat, and nothing more.
Then this ebony bird beguiling my sad fancy into smiling,
By the grave and stern decorum of the countenance it wore.
"Though thy crest be shorn and shaven, thou," I said, "art sure no craven,
Ghastly grim and ancient raven wandering from the Nightly shore -
Tell me what thy lordly name is on the Night's Plutonian shore!"
Quoth the Raven, "Nevermore."
Much I marvelled this ungainly fowl to hear discourse so plainly,
Though its answer little meaning- little relevancy bore;
For we cannot help agreeing that no living human being
Ever yet was blest with seeing bird above his chamber door -
Bird or beast upon the sculptured bust above his chamber door,
With such name as "Nevermore."
But the raven, sitting lonely on the placid bust, spoke only
That one word, as if his soul in that one word he did outpour.
Nothing further then he uttered- not a feather then he fluttered -
Till I scarcely more than muttered, "other friends have flown before -
On the morrow he will leave me, as my hopes have flown before."
Then the bird said, "Nevermore."
Startled at the stillness broken by reply so aptly spoken,
"Doubtless," said I, "what it utters is its only stock and store,
Caught from some unhappy master whom unmerciful Disaster
Followed fast and followed faster till his songs one burden bore -
Till the dirges of his Hope that melancholy burden bore
Of 'Never - nevermore'."
But the Raven still beguiling all my fancy into smiling,
Straight I wheeled a cushioned seat in front of bird, and bust and door;
Then upon the velvet sinking, I betook myself to linking
Fancy unto fancy, thinking what this ominous bird of yore -
What this grim, ungainly, ghastly, gaunt and ominous bird of yore
Meant in croaking "Nevermore."
This I sat engaged in guessing, but no syllable expressing
To the fowl whose fiery eyes now burned into my bosom's core;
This and more I sat divining, with my head at ease reclining
On the cushion's velvet lining that the lamplight gloated o'er,
But whose velvet violet lining with the lamplight gloating o'er,
She shall press, ah, nevermore!
Then methought the air grew denser, perfumed from an unseen censer
Swung by Seraphim whose footfalls tinkled on the tufted floor.
"Wretch," I cried, "thy God hath lent thee - by these angels he hath sent thee
Respite - respite and nepenthe, from thy memories of Lenore:
Quaff, oh quaff this kind nepenthe and forget this lost Lenore!"
Quoth the Raven, "Nevermore."
"Prophet!" said I, "thing of evil! - prophet still, if bird or devil! -
Whether Tempter sent, or whether tempest tossed thee here ashore,
Desolate yet all undaunted, on this desert land enchanted -
On this home by horror haunted- tell me truly, I implore -
Is there - is there balm in Gilead? - tell me - tell me, I implore!"
Quoth the Raven, "Nevermore."
"Prophet!" said I, "thing of evil - prophet still, if bird or devil!
By that Heaven that bends above us - by that God we both adore -
Tell this soul with sorrow laden if, within the distant Aidenn,
It shall clasp a sainted maiden whom the angels name Lenore -
Clasp a rare and radiant maiden whom the angels name Lenore."
Quoth the Raven, "Nevermore."
"Be that word our sign in parting, bird or fiend," I shrieked, upstarting -
"Get thee back into the tempest and the Night's Plutonian shore!
Leave no black plume as a token of that lie thy soul hath spoken!
Leave my loneliness unbroken!- quit the bust above my door!
Take thy beak from out my heart, and take thy form from off my door!"
Quoth the Raven, "Nevermore."
And the Raven, never flitting, still is sitting, still is sitting
On the pallid bust of Pallas just above my chamber door;
And his eyes have all the seeming of a demon's that is dreaming,
And the lamplight o'er him streaming throws his shadow on the floor;
And my soul from out that shadow that lies floating on the floor
Shall be lifted - nevermore!
Now it just so happens that the widow of William Morgan became one of the wives of Joseph Smith the founder of the Mormons. Now this same Smith was very deeply into what he called true and perfect masonry. He even possessed a magic amulet called the Jupiter Table. Isaac Newton was fanatically consumed in the alchemical "study" of the traditional Hermes Trismegistus' Emerald Table. (I think therefore Newton's mind might be proof of a true Tabula Rasa, in my humble opinion.)
Here is a poem exalting Hermes Trismegistus from Edgar Poe's adversary H.W. Longfellow:
"Was he one or many, merging
Name and fame in one,
Like a stream, to which, converging,
Many streamlets run ?
Who shall call his dream fallacious ?
Who has searched or sought
All the unexplored and spacious
Universe of thought ?
Who in his own skill confiding,
Shall with rule and line
Mark the border-land dividing
Human and divine ?
Trismegistus ! Three times greatest !
How thy name sublime
Has descended to this latest
Progeny to time !"
Now Joseph Glanvill's writings, which Poe so thoroughly absorbed, scored the Cabbalist Rosicrucianism in England of Kenelm Digby, et al. An ernormous amount of the mischief that has come about on these shores can be traced back to the creation of this very type of irrationalist superstition.
And The Raven is a poem that in actuality is just such a polemic (as so much of Shakespeare is likewise) against the occult and most melancholy superstition. And today many of Poe's most ardent admirers have no clue that he was and still is, in reality laughing at them.
Once upon a midnight dreary, while I pondered, weak and weary,
Over many a quaint and curious volume of forgotten lore,
While I nodded, nearly napping, suddenly there came a tapping,
As of some one gently rapping, rapping at my chamber door.
"'Tis some visitor," I muttered, "tapping at my chamber door -
Only this, and nothing more."
Ah, distinctly I remember it was in the bleak December,
And each separate dying ember wrought its ghost upon the floor.
Eagerly I wished the morrow; - vainly I had sought to borrow
From my books surcease of sorrow - sorrow for the lost Lenore -
For the rare and radiant maiden whom the angels name Lenore -
Nameless here for evermore.
And the silken sad uncertain rustling of each purple curtain
Thrilled me - filled me with fantastic terrors never felt before;
So that now, to still the beating of my heart, I stood repeating,
"'Tis some visitor entreating entrance at my chamber door -
Some late visitor entreating entrance at my chamber door; -
This it is, and nothing more."
Presently my soul grew stronger; hesitating then no longer,
"Sir," said I, "or Madam, truly your forgiveness I implore;
But the fact is I was napping, and so gently you came rapping,
And so faintly you came tapping, tapping at my chamber door,
That I scarce was sure I heard you"- here I opened wide the door; -
Darkness there, and nothing more.
Deep into that darkness peering, long I stood there wondering, fearing,
Doubting, dreaming dreams no mortals ever dared to dream before;
But the silence was unbroken, and the stillness gave no token,
And the only word there spoken was the whispered word, "Lenore?"
This I whispered, and an echo murmured back the word, "Lenore!" -
Merely this, and nothing more.
Back into the chamber turning, all my soul within me burning,
Soon again I heard a tapping somewhat louder than before.
"Surely," said I, "surely that is something at my window lattice:
Let me see, then, what thereat is, and this mystery explore -
Let my heart be still a moment and this mystery explore; -
'Tis the wind and nothing more."
Open here I flung the shutter, when, with many a flirt and flutter,
In there stepped a stately raven of the saintly days of yore;
Not the least obeisance made he; not a minute stopped or stayed he;
But, with mien of lord or lady, perched above my chamber door -
Perched upon a bust of Pallas just above my chamber door -
Perched, and sat, and nothing more.
Then this ebony bird beguiling my sad fancy into smiling,
By the grave and stern decorum of the countenance it wore.
"Though thy crest be shorn and shaven, thou," I said, "art sure no craven,
Ghastly grim and ancient raven wandering from the Nightly shore -
Tell me what thy lordly name is on the Night's Plutonian shore!"
Quoth the Raven, "Nevermore."
Much I marvelled this ungainly fowl to hear discourse so plainly,
Though its answer little meaning- little relevancy bore;
For we cannot help agreeing that no living human being
Ever yet was blest with seeing bird above his chamber door -
Bird or beast upon the sculptured bust above his chamber door,
With such name as "Nevermore."
But the raven, sitting lonely on the placid bust, spoke only
That one word, as if his soul in that one word he did outpour.
Nothing further then he uttered- not a feather then he fluttered -
Till I scarcely more than muttered, "other friends have flown before -
On the morrow he will leave me, as my hopes have flown before."
Then the bird said, "Nevermore."
Startled at the stillness broken by reply so aptly spoken,
"Doubtless," said I, "what it utters is its only stock and store,
Caught from some unhappy master whom unmerciful Disaster
Followed fast and followed faster till his songs one burden bore -
Till the dirges of his Hope that melancholy burden bore
Of 'Never - nevermore'."
But the Raven still beguiling all my fancy into smiling,
Straight I wheeled a cushioned seat in front of bird, and bust and door;
Then upon the velvet sinking, I betook myself to linking
Fancy unto fancy, thinking what this ominous bird of yore -
What this grim, ungainly, ghastly, gaunt and ominous bird of yore
Meant in croaking "Nevermore."
This I sat engaged in guessing, but no syllable expressing
To the fowl whose fiery eyes now burned into my bosom's core;
This and more I sat divining, with my head at ease reclining
On the cushion's velvet lining that the lamplight gloated o'er,
But whose velvet violet lining with the lamplight gloating o'er,
She shall press, ah, nevermore!
Then methought the air grew denser, perfumed from an unseen censer
Swung by Seraphim whose footfalls tinkled on the tufted floor.
"Wretch," I cried, "thy God hath lent thee - by these angels he hath sent thee
Respite - respite and nepenthe, from thy memories of Lenore:
Quaff, oh quaff this kind nepenthe and forget this lost Lenore!"
Quoth the Raven, "Nevermore."
"Prophet!" said I, "thing of evil! - prophet still, if bird or devil! -
Whether Tempter sent, or whether tempest tossed thee here ashore,
Desolate yet all undaunted, on this desert land enchanted -
On this home by horror haunted- tell me truly, I implore -
Is there - is there balm in Gilead? - tell me - tell me, I implore!"
Quoth the Raven, "Nevermore."
"Prophet!" said I, "thing of evil - prophet still, if bird or devil!
By that Heaven that bends above us - by that God we both adore -
Tell this soul with sorrow laden if, within the distant Aidenn,
It shall clasp a sainted maiden whom the angels name Lenore -
Clasp a rare and radiant maiden whom the angels name Lenore."
Quoth the Raven, "Nevermore."
"Be that word our sign in parting, bird or fiend," I shrieked, upstarting -
"Get thee back into the tempest and the Night's Plutonian shore!
Leave no black plume as a token of that lie thy soul hath spoken!
Leave my loneliness unbroken!- quit the bust above my door!
Take thy beak from out my heart, and take thy form from off my door!"
Quoth the Raven, "Nevermore."
And the Raven, never flitting, still is sitting, still is sitting
On the pallid bust of Pallas just above my chamber door;
And his eyes have all the seeming of a demon's that is dreaming,
And the lamplight o'er him streaming throws his shadow on the floor;
And my soul from out that shadow that lies floating on the floor
Shall be lifted - nevermore!
Saturday, May 12, 2012
Is the Good Doctor Leonard Suskind Off His Rocker?
I have had much merriment in this blogosphere for some time now lampooning the absurdities of theoretical physicists. The egregious character of Sheldon Cooper on TV's The Big Bang Theory must seem a stretch to some, however I fear the comedy doesn't quite do justice to real life. We all smile, of course, when we hear about the recondite Aristotelian scholastics who got their knickers in a twist over how many angels can fit on a pinhead. But now I am starting to fear for these fine feathered fellows' sanity when I come across such wild-eyed stuff as this: (But perhaps there be financial method and rewards to their madness...)
Is Eternal Inflation Past-Eternal? And What if It Is?
Leonard Susskind
(Submitted on 3 May 2012)
As a result of discussions with Bousso and Vilenkin I want to return to the question of whether the multiverse is past-eternal or if there was a beginning. Not surprisingly, given three people, there were three answers. However, the discussions have led to some common ground.
The multiverse being past-eternal, or at least extremely old has content and potential phenomenological implications. I will discuss how the oldness of the multiverse is connected with recent speculations of Douglas.
Is Eternal Inflation Past-Eternal? And What if It Is?
Leonard Susskind
(Submitted on 3 May 2012)
As a result of discussions with Bousso and Vilenkin I want to return to the question of whether the multiverse is past-eternal or if there was a beginning. Not surprisingly, given three people, there were three answers. However, the discussions have led to some common ground.
The multiverse being past-eternal, or at least extremely old has content and potential phenomenological implications. I will discuss how the oldness of the multiverse is connected with recent speculations of Douglas.
Information "Theory" is Nothing Except Fraud and Mysticism
Here comes a rather self important and "weighty" arXiv paper claiming to clarify the confusion regarding self organizing complex systems. While "cellular automata" are the solitonic type of phenomena which I have emphasized are well worth study, the ridiculous conceit that these types of phenomena can reduced to some network input /output computer model is laughable. Read the synopsis for a chuckle or two, if you please:
Complexity and Information: Measuring Emergence, Self-organization, and Homeostasis at Multiple Scales
Carlos Gershenson, Nelson Fernandez
(Submitted on 9 May 2012)
Concepts used in the scientific study of complex systems have become so widespread that their use and abuse has led to ambiguity and confusion in their meaning. In this paper we use information theory to provide abstract and concise measures of complexity, emergence, self-organization, and homeostasis. The purpose is to clarify the meaning of these concepts with the aid of the proposed formal measures. In a simplified version of the measures (focussing on the information produced by a system), emergence becomes the opposite of self-organization, while complexity represents their balance. We use computational experiments on random Boolean networks and elementary cellular automata to illustrate our measures at multiple scales.
Complexity and Information: Measuring Emergence, Self-organization, and Homeostasis at Multiple Scales
Carlos Gershenson, Nelson Fernandez
(Submitted on 9 May 2012)
Concepts used in the scientific study of complex systems have become so widespread that their use and abuse has led to ambiguity and confusion in their meaning. In this paper we use information theory to provide abstract and concise measures of complexity, emergence, self-organization, and homeostasis. The purpose is to clarify the meaning of these concepts with the aid of the proposed formal measures. In a simplified version of the measures (focussing on the information produced by a system), emergence becomes the opposite of self-organization, while complexity represents their balance. We use computational experiments on random Boolean networks and elementary cellular automata to illustrate our measures at multiple scales.
Tuesday, May 08, 2012
How a Magical Belief in Entropy Makes Us Blind
Life scientists unlock mystery of how 'handedness' arises
Colored patches represent parallelogram outlines around pairs of triangles that have formed chiral super-structures. Parallelograms having different "handedness" and orientations are color-coded and superimposed over each other. Credit: Thomas G. Mason and Kun Zhao
The overwhelming majority of proteins and other functional molecules in our bodies display a striking molecular characteristic: They can exist in two distinct forms that are mirror images of each other, like your right hand and left hand. Surprisingly, each of our bodies prefers only one of these molecular forms.
This mirror-image phenomenon -- known as chirality or "handedness" -- has captured the imagination of a UCLA research group led by Thomas G. Mason, a professor of chemistry and physics and a member of the California NanoSystems Institute at UCLA.
Mason has been exploring how and why chirality arises, and his newest findings on the physical origins of the phenomenon were published May 1 in the journal Nature Communications.
"Objects like our hands are chiral, while objects like regular triangles are achiral, meaning they don't have a handedness to them," said Mason, the senior author of the study. "Achiral objects can be easily superimposed on top of one another."
Why many of the important functional molecules in our bodies almost always occur in just one chiral form when they could potentially exist in either is a mystery that has confounded researchers for years.
"Our bodies contain important molecules like proteins that overwhelmingly have one type of chirality," Mason said. "The other chiral form is essentially not found. I find that fascinating. We asked, 'Could this biological preference of a particular chirality possibly have a physical origin?'"
In addressing this question, Mason and his team sought to discover how chirality occurs in the first place. Their findings offer new insights into how the phenomenon can arise spontaneously, even with achiral building-blocks.
Mason and his colleagues used a manufacturing technique called lithography, which is the basis for making computer chips, to make millions of microscale particles in the shape of achiral triangles. In the past, Mason has used this technique to "print" particles in a wide variety of shapes, and even in the form of letters of the alphabet.
Using optical microscopy, the researchers then studied very dense systems of these lithographic triangular particles. To their surprise, they discovered that the achiral triangles spontaneously arranged themselves to form two-triangle "super-structures," with each super-structure exhibiting a particular chirality.
In the image that accompanies this article, the colored outlines in the field of triangles indicate chiral super-structures having particular orientations.
So what is causing this phenomenon to occur? Entropy, says Mason. His group has shown for the first time that chiral structures can originate from physical entropic forces acting on uniform achiral particles.
"It's quite bizarre," Mason said. "You're starting with achiral components — triangles — which undergo Brownian motion and you end up with the spontaneous formation of super-structures that have a handedness or chirality. I would never have anticipated that in a million years."
Entropy is usually thought of as a disordering force, but that doesn't capture its subtler aspects. In this case, when the triangular particles are diffusing and interacting at very high densities on a flat surface, each particle can actually maximize its "wiggle room" by becoming partially ordered into a liquid crystal (a phase of matter between a liquid and a solid) made out of chiral super-structures of triangles.
"We discovered that just two physical ingredients — entropy and particle shape — are enough to cause chirality to appear spontaneously in dense systems," Mason said. "In my 25 years of doing research, I never thought that I would see chirality occur in a system of achiral objects driven by entropic forces."
As for the future of this research, "We are very interested to see what happens with other shapes and if we can eventually control the chiral formations that we see occurring here spontaneously," he said.
"To me, it's intriguing, because I think about the chiral preference in biology," Mason added. "How did this chiral preference happen? What are the minimum ingredients for that to occur? We're learning some new physical rules, but the story in biology is far from complete. We have added another chapter to the story, and I'm amazed by these findings."
To learn more, a message board accompanies the publication in Nature Communications, an online journal, as a forum for interactive discussion.
This research was funded by the University of California. Kun Zhao, a postdoctoral researcher in Mason's laboratory, made many key contributions, including fabricating the triangle particles, creating the two-dimensional system of particles, performing the optical microscopy experiments, carrying out extensive particle-tracking analysis and interpreting the results.
If it were simply entropy, how and by what circumstance did the close packing occur? Entropy again?
So what we have here is a recursive reductio ad absurdum species of mathematical supposition which takes entropy as a given that somehow miraculously always leads to less and less disorder. Cannot we see the fallacy of composition in the premises of reasoning here?
In fact, the quality of step function increases in the living processes in the biosphere to both capture and organize energy in increasing density of throughput to ever higher states of evolution is evidence not of entropy but the very opposite.
This evolution culminates in the human species ability to consciously change its mode of capture and organization of energy via creative problem solving expressed in technology. Once again, further devastating evidence that negative entropy is the subsuming potential latent in the universal process of development, not stochasticity or for that matter irrationality...
Monday, May 07, 2012
Winter of Financiers' Discontent
What dark and nasty thoughts must be roiling around in the skulls of the oligarchy today? It must be something to the effect that "democracy must be upended"
" Fiscal austerity cannot ever win elections and must simply be imposed. Oh, if only the people would come to see this simple fact of life, dictatorships would be unnecessary. But no, they never learn. Now we will need to scour the field for strong men to bring the rabble to heel. So be it."
" Fiscal austerity cannot ever win elections and must simply be imposed. Oh, if only the people would come to see this simple fact of life, dictatorships would be unnecessary. But no, they never learn. Now we will need to scour the field for strong men to bring the rabble to heel. So be it."
Sunday, May 06, 2012
Abraham Lincoln's Assassination, Colley Cibber, Alexander Pope and Jonathan Swift
When Lincoln complained about the removal of a pivotal soliloquy from Shakespeare's Richard III "Now is the winter of our discontent, " he perhaps inadvertently took aim at Alexander Pope's "dunce" Colley Cibber. It was Cibber who played fast and loose with the Bard, in his day, giving way to the base peculiarities of popular sentiment for a pretty speech.
Pope, that ally of very same Jonathan Swift who has reached out from the grave, as it were, to indite Prince Phillip and his Malthusian oligarchic ilk in their bestial hatred of the procreation of "useless eaters," with his great satire "A Modest Proposal." Pope and Lincoln were linked in their revulsion against the liberties that Cibber took that mocked the sense of Shakespeare for mere "sound and fury" loved by the mob.
Swift, who did everything in his power to thwart the evil designs of the British Empire against his beloved Ireland through his influence over Queen Anne. And in his exposure in Gulliver of the British colonial method of a war of "each against all," he limned a great lesson for our yet to be Republic.
How tragically à propos was it then that a lunatic conspirator, and product of Colley Cibber's "dumbing down" of Shakespeare, John Wilkes Booth, should be the instrument of such evil? Had Lincoln lived, it is nearly a certainty that he would have taken the war against Britain "carried forthwith into Africa."
Pope, that ally of very same Jonathan Swift who has reached out from the grave, as it were, to indite Prince Phillip and his Malthusian oligarchic ilk in their bestial hatred of the procreation of "useless eaters," with his great satire "A Modest Proposal." Pope and Lincoln were linked in their revulsion against the liberties that Cibber took that mocked the sense of Shakespeare for mere "sound and fury" loved by the mob.
Swift, who did everything in his power to thwart the evil designs of the British Empire against his beloved Ireland through his influence over Queen Anne. And in his exposure in Gulliver of the British colonial method of a war of "each against all," he limned a great lesson for our yet to be Republic.
How tragically à propos was it then that a lunatic conspirator, and product of Colley Cibber's "dumbing down" of Shakespeare, John Wilkes Booth, should be the instrument of such evil? Had Lincoln lived, it is nearly a certainty that he would have taken the war against Britain "carried forthwith into Africa."
The Beautiful Puritan Pansies: Glanvill, Mather, Franklin, Beethoven, Cusa, Toscanelli, Columbus
Edgar Allan Poe's Virgil was to a degree Joseph Glanvill. The title alone of his work "Scepsis scientifica: or, Confest Ignorance the way to science" fairly leaps off the page for any who have read Nicolas of Cusa's Of Learned Ignorance.
It is of no little moment then, that Cotton Mather's whose Essays To Do Good literally were the inspiration of none other than the subject Beethoven's Ode to Joy "Gotterfunken" Benjamin Franklin!
For it was Cusa and Toscanelli that enabled Christopher Columbus to set off for this "New World." And remarkably, the Massachusetts Charter is in this sense an offshoot of that same spirit of learned ignorance. One has but to begin to read Mather's American Bible to comprehend the profound impact of the quest for scientific progress inherent in the purpose of the Revolution.
It is of no little moment then, that Cotton Mather's whose Essays To Do Good literally were the inspiration of none other than the subject Beethoven's Ode to Joy "Gotterfunken" Benjamin Franklin!
For it was Cusa and Toscanelli that enabled Christopher Columbus to set off for this "New World." And remarkably, the Massachusetts Charter is in this sense an offshoot of that same spirit of learned ignorance. One has but to begin to read Mather's American Bible to comprehend the profound impact of the quest for scientific progress inherent in the purpose of the Revolution.
More Sunday Funnies
Well, well. Once again it has been borne out that the effrontery of the statisticians is without limit. This very risible title, that is for the cognoscenti amongst us, has just found its way across Thingumbob's computer screen:
"No Fundamental Limitation on Studying Living Organisms and Other Complex Systems with Statistical Methods"
"No Fundamental Limitation on Studying Living Organisms and Other Complex Systems with Statistical Methods"
What a sense of humor this mathematician must have to publish this. Oh tell me where muse, is the good Reverend Jonathan Swift gone to in our hour of direst need?
The Ugly Truth About Gertrude Stein
Much like the excellent example of Poe's purloined letter, the truth has been there all along. Liberals make the best fascists. They simply cannot help themselves.
It is a not so bewildering fact that must confront most, if not all, sentient baby boomers, that side by side with their protest songs, a rather sleazy love affair in academe was being had all the while for the icons of fascism-- Wagner, Nietsche, Ezra Pound, Gertrude Stein...No, this wasn't your hardcore right wing Joe McCarthy stuff.
Do what thou wilt! If mass murder a la Charles Manson be thy thing,, so be it! All is groovy...
It is a not so bewildering fact that must confront most, if not all, sentient baby boomers, that side by side with their protest songs, a rather sleazy love affair in academe was being had all the while for the icons of fascism-- Wagner, Nietsche, Ezra Pound, Gertrude Stein...No, this wasn't your hardcore right wing Joe McCarthy stuff.
Do what thou wilt! If mass murder a la Charles Manson be thy thing,, so be it! All is groovy...
Saturday, May 05, 2012
The Astounding Protein Vectored Topology of Cell Membranes
In Nicholas of Cusa's conception of the ongoing becoming of the microcosm that emulates the macrocosmic, the kernel of Leibniz' monads and Vernadsky's spheres is adumbrated. The recent remarkable discovery of domains of proteins in the organization of the cellular membrane should be understood in the larger context of bearing out the relevance of that tradition. If scientists only understood why the necessary ordering of the biosphere occurs everywhere in this manner of developing progress would proceed with a dizzying speed.
(Phys.org) -- As the interface between the cell and its environment, the cell membrane, which consists of fats and proteins, fulfils a variety of vital functions. Scientists at the Max Planck Institute of Biochemistry in Martinsried near Munich have performed the first comprehensive analysis of the molecular structure of this boundary layer, and revealed precisely how it is organised. In yeast cells, the entire membrane is made up of independent domains, each containing just one or a few protein types. If a protein is relocated to an inappropriate domain, it may even fail to function. The study shows that the membrane is a kind of patchwork quilt and should help scientists to gain a better understanding of basic cellular processes.
(Phys.org) -- As the interface between the cell and its environment, the cell membrane, which consists of fats and proteins, fulfils a variety of vital functions. Scientists at the Max Planck Institute of Biochemistry in Martinsried near Munich have performed the first comprehensive analysis of the molecular structure of this boundary layer, and revealed precisely how it is organised. In yeast cells, the entire membrane is made up of independent domains, each containing just one or a few protein types. If a protein is relocated to an inappropriate domain, it may even fail to function. The study shows that the membrane is a kind of patchwork quilt and should help scientists to gain a better understanding of basic cellular processes.
Friday, May 04, 2012
Leonardo: Artist or Scientist?
These arguments are, in the end, ludicrously childish. Although the straw man argument of Newton's alchemy is amusing... ((For example, Newton (in juxtaposition to Leibniz) indeed was a quack! A quack who believed, (among other imbecilities) that the text of the Bible foretold the date of the end of the world based upon a hidden secret code therein.)) The idea that reality can be defined via mere words is nominalism. This is wildly irrational. The desire to put a label on the works of Leonardo and catalog him as in a sort of human zoo is nominalism: it signifies nothing..that is, except superstitious ignorance.
Leonardo won a contest performing as a musician, singing and playing the lute in Florence. He was sent as an emissary of sorts by Lorenzo the Magnificent of Florence to the court of Sforza Duke of Milan. To whom, it was reported, Leonardo proffered a magnificent silver lute of his own design. So really, I believe, you fine fellows have it all wrong. He was really a musician...or was it a designer of theatrical displays?
Thursday, May 03, 2012
HSBC Laundering Drug Money-Quelle Surprise!
Oh come off it, Reuters! Anyone who has a smattering acquaintance of the history of the Opium Wars knows Jardine Matheson Hong Kong Shanghai Baank was in the middle of the drug trade forever. This was absolutely predictable. The laundering of drug money profits is the City of London's stock in trade time immemorial.
Why do you think that the drug promoting rock and roll icons have all been knighted by "her royal majesty?"
Why do you think that the drug promoting rock and roll icons have all been knighted by "her royal majesty?"
Tuesday, May 01, 2012
Biology Subdues Randomness
Although these researchers use the mathematics and method of apparent "randomness," the fact is that the organic biosphere at the level of the "infinitesimal" is a vectored process of development in opposition to the limits imposed by the inorganic lithosphere. While the quality of twist induced in the electrostatic field may appear as merely a mechanical epiphenomenon, there exists a type of unique biophysical conatus behind this.
Electric charge disorder: A key to biological order?
Strong attraction that arises between biological objects with random patches of electric charge on an otherwise neutral surface may partly explain pattern recognition in biology
Theoretical physicist Ali Naji from the IPM in Tehran and the University of Cambridge, UK, and his colleagues have shown how small random patches of disordered, frozen electric charges can make a difference when they are scattered on surfaces that are overall neutral. These charges induce a twisting force that is strong enough to be felt as far as nanometers or even micrometers away. These results, about to be published in EPJ E¹, could help to understand phenomena that occurr on surfaces such as those of large biological molecules.
To measure the strength of the twist that acts on a randomly charged surface, the authors used a sphere which was mounted like a spinning top next to a randomly charged flat substrate. Because small amounts of positive and negative charges were spread in a disordered mosaic throughout both surfaces, they induced transient attractive or repulsive twisting forces. This was regardless of the surfaces’ overall electrical neutrality, thus making the sphere spin. Using statistical averaging methods, the authors studied the fluctuations of these forces.
The authors found that the twisting force, created by virtue of the disorder of surface charges, is expected to be much stronger and far-reaching than the remnant forces. The latter are always present, even in the absence of charge disorder, and are due to fluctuations at the atomic and molecular levels.
This could have implications for large randomly charged surfaces such as biological macromolecules, which may be exposed to strong electrostatic forces, inducing attraction and/or repulsion, even if they carry no overall net charge. For instance, this phenomenon could partly explain biological pattern recognition, such as lock and key phenomena. In that context, the twisting force could explain the attraction between biological macromolecules that lead to pre-alignment prior to their interaction.
Simple Question About Chris Christie
Some wag in our midst might be prone to asking this burning (as in indigestion) question: is it possible for that august and venerable American electorate to get our metaphorical collective arms around a Chris Christie run (as if running in itself weren't too much to ask) for Vice President? Let us all chew the fat on this anon...
Obama Romney Bin Laden
Well, I suppose the next step in this tragicfarce mano a mano circus will no doubt be a pledge to use nuclear bombs against Iran. Remarkably breathtaking this rather sordid kind of insanity that grips our so called politics these days!
The Terminally Ill Philosophy
For those poor wights that purchase their servitude to the moneyed powers by assenting to the wretched and forlorn belief that humans are but talking animals, it must seem that life is but a short, maddening and dull flicker of a terminal illness.
However, those few who truly know that the entire mission of the whole history of mankind is uniquely in conformity with immortality's potential. These alone have emerged from the invidious grip of the chains of self delusion.
However, those few who truly know that the entire mission of the whole history of mankind is uniquely in conformity with immortality's potential. These alone have emerged from the invidious grip of the chains of self delusion.
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- Obama's Brain on Marijuana
- Christine Lagarde: The Face of Evil
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- Is the Good Doctor Leonard Suskind Off His Rocker?
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- How a Magical Belief in Entropy Makes Us Blind
- Winter of Financiers' Discontent
- Abraham Lincoln's Assassination, Colley Cibber, Al...
- The Beautiful Puritan Pansies: Glanvill, Mather, F...
- More Sunday Funnies
- The Ugly Truth About Gertrude Stein
- The Astounding Protein Vectored Topology of Cell M...
- Leonardo: Artist or Scientist?
- HSBC Laundering Drug Money-Quelle Surprise!
- Biology Subdues Randomness
- Simple Question About Chris Christie
- Obama Romney Bin Laden
- The Terminally Ill Philosophy
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