Proteins and Biophysical Manifolds

Today we are witnessing a welter of recently designated functional biophysical domains as "omes," mostly conventionally named after the genome. My question is whether there is a unifying principle that can help to bring these rigorously and coherently together.

We are now very much in the infancy of beginning to apprehend how the so called junk DNA transposons may operate in a regulatory manner, for instance, over the protein "interactome." I have been fascinated as a layman who has studied physical economics (as opposed to monetarism) and epistemology for many years with connection of energy dynamics in evolutionary biophysics. 

So I began to look at the powerhouse of the enzyme ATPase as the engine of cellular energy production and throughput. It struck me as remarkable that there was a rotational vector for this that changed chiral handedness depending on whether the cell's respiration was aerobic or non aerobic. So that this was an instance of the Pasteur principal that characterized life at this level.

This led me to view the rationale of Vernadsky's division of the three interacting spheres of physical, biological and human creative powers as being potentially unified around unique forms of functional organization. The transmission of particularly long lived metastable solitonic wave organizations in the inorganic domain seemed to parallel life in a sense. Further the directed quality of many anomalies in astrophysical organization as opposed to the assumptions of chaotic, stochastic entropy. In other words, is there an immanent tendency in this realm for the evolutionary development of life. Why should we suppose anything else? 

Of late, the ideas of Bernhard Riemann with respect to Non-Euclidean constructive geometry coupled with his work on shockwaves have led me to propose a pathway toward a possible unifying geometry of biophysics. Firstly, the protein acts as a singularity through which one or more biological functions operate. This to me was very strikingly similar to the Riemannian arrangement of functional space into connected surfaces of branchpoints that go through singular poles to sheets of a potential variety of functions. Thus the various "omes" mentioned above may be viewed as connected in this way. 

Secondly, I have proposed that the principle of transmission of energy in the biosphere leads under certain circumstances to evolutionary change. The revolutionary seminal work that Riemann did on pressure waves as they surpass the boundary of transmissibility leading to the well known sonic boom and Mach cone guided my thoughts here.