"The mind is a compact, multiply connected thought mass with internal connections of the most intimate kind. It grows continuously as new thought masses enter it, and this is the means by which it continues to develop."

Bernhard Riemann On Psychology and Metaphysics ca. 1860

"It is clear that the minds are the most important part of the universe, and that everything was established for their sake; that is, in choosing the order of things, the greatest account was taken of them; all things being arranged in such a way that they appear the more beautiful the more they are understood."

G. W. Leibniz

Today's Elites


Saturday, October 30, 2010

Genomic Organization Proven To be Non-Random

As the recurring theme here attests, it is the author's delight to put the purveyors of a-causal randomness to flight. It is with great joy that I welcome some recent research on nucleic acid three dimensional structure of yeast that does just that. I quote some relevant excerpts below. But please read the entire contents for details.

Eukaryotic genomes are non-randomly organized in the nucleus. It is becoming clear that intra-nuclear positions of genomic loci are influenced by various nuclear processes including transcription, replication and repair... It has recently been suggested that transcription factors are involved in the association of genes with these transcription factories. However, how transcription factories function remains unclear, partly because they have been studied in complex mammalian cells. Studying the factories in a model organism with a much simpler genome can facilitate understanding of the role of transcription factories with regard to transcriptional regulation.



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