"The mind is a compact, multiply connected thought mass with internal connections of the most intimate kind. It grows continuously as new thought masses enter it, and this is the means by which it continues to develop."

Bernhard Riemann On Psychology and Metaphysics ca. 1860

Today's Elites


Saturday, October 29, 2011

Democrats on Super Committee Plan for Savage Austerity on the Most Defenseless

The Wall Street speculators used the Clinton administration's ever so brilliant tactic of "triangulation" to repeal FDR's Glass-Steagall banking regulations thereby creating worthless trillions of dollars of unregulated derivative securities. This treachery is what sunk public finances.  Now Wall Street demands fascist austerity and the toady "Democrats" rush to implement it in lockstep, why should any but the most gullible mush-headed Pollyannas be surprised?

Saturday, October 22, 2011

The Winning Essay on Population

Thingumbob's entry in today's weighty query from the editors of that most august organ of liberalism everywhere, the Economist, is a marvel of laconic and yet perfectly applied Yankee ingenuity, in my most humble opinion. To the point at once then.

They ask "On October 31st the UN will dub a newborn the world’s 7 billionth living person. Is the world overcrowded?" (Adding in the kicker: "Persuading women to have fewer babies would help in some places. But it is no answer to scarce resources.")

Yours truly, in the spirit of the most Reverend Jonathan Swift, rejoins thusly: "Is the world overcrowded? Only with royals...only with royals."


Friday, October 21, 2011

The Essence of Change

The universal law of dynamics is nonlinear growth. The spiral form of that growth that is presented to humanity across domains and scales ranging from the infinite to the infinitesimal bespeaks a power that finds its epitome only in the sublime beauty that rules our imagination.



The cochlea is a spiral-shaped tunnel in the bony labyrinth of the inner ear. Its principal component is a strip of sensory tissue (red) called the organ of Corti. The organ of Corti is lined with rows of auditory hair cells. Hair bundles that project from the hair cells are deflected in response to sound-induced vibrations in the basilar membrane. This bending opens mechanically gated ion channels, initiating the conversation of the sound-induced mechanical stimulus into an electrical transmission
.M'hamed Grati and Bechara Kachar, NIDCD/NIH

Sunday, October 16, 2011

The Cain Mutiny

Today's WAPO portrays Cain as a puppet of the notorious Koch brothers.

Yours truly being truly fair and balanced, unlike the trash from Fox or MSNBC, did enter the lists on a lively verbal tussle of give and take. Here are some lowlights:

Thingumbob: What has really changed since emancipation? The Koch brothers own Cain and Soros owns Obama...So sad.

OldUncleTom: It would be interesting if you could make any case at all for a connection between George Soros and Barack Obama that is half as tangible as that between AFP/Koch Industries and Herman Cain.
For the record, citations from the "Hannity" show don't count. His opinions are about as relevant as yours are.

Thingumbob: So you really are convinced that Obama isn't doing the bidding of Wall Street? What about Gethner? They, Cain or Obama are just different flavors of the same old all day suckers. Sorry you can't see this.

OldUncleTom: Changing the subject does not negate the ridiculous first statement you made, sport.
Nice try, though!

Thingumbob: By the way. I detest both MSNBC and Fox because they are just opposite sides of the same worthless coin. Only dupes of Wall Street believe there is a dimes worth of difference. The speculators are being bailed out over our dead bodies, Obama and Cain are both tissue paper for those scoundrels. Again, if you don't see that then the old adage applies that there are none so blind as those that will not see...

Thingumbob: Ask Obama Mr. liberal OldUncleTom why he doesn't support Marcy Kaptur's legislation to restore FDR's Glass Steagall and why he is using the Patriot Act to spy on and assassinate more Americans even than Cheney.

...


Thingumbob:What are we to think? Cain a mere puppet for the Koch brothers, and Obama a puppet for Soros? So hard to choose one over the other...

OldUncleTom:There is a huge difference between being supported by many wealthy liberals and being owned by two wealthy conservatives.

Thingumbob: Well you could'a fooled me...Exactly what is Obama doing to bite the hand that feeds him? He is the same and worse than W in my book and I ain't no neocon.


Viewoflife: sorry, bush 2 was by far the worst president ever, but cheney probably had something to do with that.

Thingumbob: Haven't you heard that Cheney loves Obama's killing of Americans overseas without so much as an arrest warrant? Again, who do you think you are fooling but yourself?

5amefa91:Yep, Obama sold out to the consevatards Kochroaches

...

Thingumbob: If the Kochs' boy Cain runs against Soros' boy Obama, it won't be an election, it will be an auction.

Soaked in Bloody Irony

While the Occupy Wall Street protests proceed apace, how ironic of him that Obama is now occupying Africa for Wall Street. Must be tickling the likes of Henry Kissinger pink. The very same Kissinger who declared that population growth of Africa was a national security threat to the U.S. (Of course he meant the City of London and their junior epigones (or perhaps better put-- apes) on Wall Street.)
(It Seems that George Washington Looks Askance in Disgust at This Motley Crew: Shultz, Kissinger, and the One. Who is More Loyal to HRH? Or Will Obama Also Be Knighted, or Just Benighted?)

Saturday, October 15, 2011

Micro RNAs and Biophysics Methodology

This research is indicative of the continuing overturning of dogma regarding simple point mutation of genes and disease. I wrote here in 2009 that the complex interaction of a protein multi functional network was reminiscent of a Riemann surface branch point function. The further discovery of the functional network of RNA/DNA interactions adds to this perspective:


Interactions Regulates Established Oncogenic Pathways in Glioblastoma

  To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect.
Cell, Volume 147, Issue 2, 370-381, 14 October 2011
Copyright © 2011 Elsevier Inc. All rights reserved.
10.1016/j.cell.2011.09.041

Authors

  • Highlights
  • Computational inference reveals a network of miR-mediated interactions in glioblastoma
  • These interactions regulate thousands of genes, including oncogenes and tumor suppressors
  • These interactions regulate miR targets without affecting miR expression
  • These interactions enable crosstalk between established oncogenic pathways

Summary

By analyzing gene expression data in glioblastoma in combination with matched microRNA profiles, we have uncovered a posttranscriptional regulation layer of surprising magnitude, comprising more than 248,000 microRNA (miR)-mediated interactions. These include ∼7,000 genes whose transcripts act as miR “sponges” and 148 genes that act through alternative, nonsponge interactions. Biochemical analyses in cell lines confirmed that this network regulates established drivers of tumor initiation and subtype implementation, including PTENPDGFRARB1VEGFASTAT3, and RUNX1, suggesting that these interactions mediate crosstalk between canonical oncogenic pathways. siRNA silencing of 13 miR-mediated PTEN regulators, whose locus deletions are predictive ofPTEN expression variability, was sufficient to downregulate PTEN in a 3′UTR-dependent manner and to increase tumor cell growth rates. Thus, miR-mediated interactions provide a mechanistic, experimentally validated rationale for the loss of PTEN expression in a large number of glioma samples with an intact PTEN locus.

Einstein Vindicated

Einstein's concept of  invariance of the speed of light and relativity has been upheld. The neutrino paradox is no more. One thing to keep in mind though, is that the quality of what we refer to as light is also relative not merely to a frame of physical reference. Which is to say, that light operates across the interacting domains or spheres (per Vernadsky) of the non living, living, and noetic. It is no accident therefore that "light" is a self reflective and perfect metaphor across all human languages.
Laser solitonic "light bullets"

Wednesday, October 12, 2011

Brilliant Research In the Tradition of Louis Pasteur


Peanut allergy turned off by tricking immune system


Researchers have turned off a life-threatening allergic response to peanuts by tricking the immune system into thinking the nut proteins aren't a threat to the body, according to a new preclinical study from Northwestern Medicine. The peanut tolerance was achieved by attaching peanut proteins onto blood cells and reintroducing them to the body -- an approach that ultimately may be able to target more than one food allergy at a time.

Monday, October 10, 2011

A Prime Example of Why True Science Is Not Based on Sense Certainty


 A Strange Sunrise Over Argentina 
Image Credit & Copyright: Luis Argerich
Explanation: Why would a rising Sun look so strange? No one is yet sure. What is clear is that the above unusual sunrise was captured last month from Buenos AiresArgentina. The body of water in the foreground is Rio de La Plata, considered by many to be the widest river in the world. Although the above image is actually a combination of a normal and a very short exposure needed to avoid oversaturating the bright Sun, the photographer saw this unusual structure with his own eyes, indicating that this effect was caused by neither reflections nor distortions in the camera or lens. What looks like arms on this monster illusion might actually be, for example, low level clouds just thick enough to scatter sunlight without completely blocking the Sun. Additionally, the distortion visible on the lower part of the Sun's image might indicate a Etruscan Vase or Fata Morgana mirage possibly created by a curious refracting layer of air over the water. Unusual atmospheric phenomena are frequently thrilling to see personally, and although most can be traced to well known phenomena, others, for lack of more data, remain mysterious.

Saturday, October 08, 2011

Twinkle Twinkle Little Crab Nebula Pulsar

Anomalies are the soul of the universal raison d'être, the which, we must take heart, will never come to an end for as long as the immanent self reflective property of this finite, unbounded universe shall continue. And the question of the non obedience of the Crab Pulsar with the cold and dead algebraic formulism that denies the possibility of its gamma ray energetics is concerned, the man who declared that the new astronomy was about fathoming the mind of the Creator, Johannes Kepler aptly stated in his preface to the revolutionary work Harmonices Mundi, "But I deal with these types by the reasoning of the mind, not by numbers, and not by algebra."


Chandra's Xray Image of the Crab Pulsar Anomaly

Mr. Obama's Troubles May Offer Some Hope For the Un-Wall Street Rest of Us

Now, I can't say that the Solyndra and Fast and Furious affairs haven't been set in motion in order to climax precisely with the reelection campaign of Mr. Soros' boy, but it sure looks that way.
Here is a sign of the times that shows Obama's charade as a "class warrior" is wearing extremely thin:

Thursday, October 06, 2011

City Planning

Imagining that the centuries of detritus of the control by an oligarchy that ruled by playing on humankind's terror of mortality has been swept aside, what glimmerings of things to come can we glean from where we are now? If we look at the tendency for science in the improvement of use and development in extending and comprehending electromagnetic waveforms, we are most likely to succeed.

For example, even given the early and primitive development of usage of GPS and electrode brainwave decoding, it were foreseeable that just like fingerprints each living and non living "process" might be located and "communicated" with by each other. Imagine an extremely large artificial planetoid in the dimly conceived of future, operating on what we now barely know as antimatter fuel that inherently possesses this marvelous evolving  platform for unleashing the underlying poetic, harmonic beauty that we dream humanity must possess.

Such a vision would be a worthy successor to Leonardo's architectural deign for the perfect concert hall.
The Adoration of the Magi

Tuesday, October 04, 2011

Analog Wave Forms Versus Digital "Information" Models of the Brain

Two recent studies reinforce my previous hypotheses regarding the underlying biophysical meta-stable soliton shockwave nature of brain/mind duality. The first study  from MIT showed that in rats the peak of oscillatory brain waves coincide with the activity of successful problem solving.

This coheres with what I have adduced from the principle embedded in Riemann's work on supersonic shockwaves. To wit: the pre-existing medium of activity is transparent for learned behaviors but must be somehow transformed to allow for new previously unknown behaviors. The wave forms associated with this new process are travelling faster than the medium can transmit. Therefore the oscillations bunch up and the medium undergoes a  transformation via induced plasticity. Once that occurs, the medium is now transparent to the newly learned behavior. (The use of a rat's brainwaves, of course only provides an extremely crude biophysical substrate for human "learning.")

The second study from UCLA, whether the said researchers are aware of it or not, provides a devastating refutation of so-called connectionist artificial intelligence brain network models.

Rather than presupposing a fatuously crude base 2 input-output, on-off "deep grammar" model for neuronal function, it proceeds from the actual physical evidence that there are harmonically tuned analog wave forms that are optimized for maximal learning.

The puerile attempt to model human thought, let alone lower forms of mammalian mental behavior, from the standpoint of a digital model is inherently fallacious because mathematics itself is not and can never be a substitute for the process of universal harmonic, and in the case of humanity, willful, ongoing self development. To coin a phrase, the very neurons and dendrites cry out this truth. 

Sunday, October 02, 2011

Jokers to The Left AND Right

"Gee, aren't you the fellows who, when you buy a company, do something called "due diligence"? But you sunk everything into stock in Obamania Inc. on the basis of his "perfectly creased pant leg" or whatever David Brooks was drooling about that day? You handed a multitrillion-dollar economy to a community organizer and you're surprised that it led to more taxes, more bureaucracy, more regulation, more barnacles on an already rusting hulk?"


The above quote comes from a financial blogger named Mark Steyn. This is an example of complete and utter misdirection. The Obama administration is completely opposed to a man to re-regulating Wall Street. In fact, they have continued and worsened the derivatives deregulation nightmare. Too big to fail is the credo of helicopter Ben Bernanke, Geithner, and Summers, inter alia. The creative financial scams have made these pols, Obama included. They have looted and continue to loot the unwashed masses. If Obama is used up, it's only because his tissue of lies as a front man for Wall Street has become all too transparent. 

Note to Wall Street Demonstrators

We the people will take you seriously as soon as anyone among your number has the guts to carry a sign saying "Impeach Obama Wall Street's Stooge."

Saturday, October 01, 2011

More Political Predictions

Should Chris Christie decide to jump into the pool of Presidential hopefuls at this late date, pundits predict it will create a veritable political tsunami.

Blog Archive